Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 8/20 | 0.66 |
| ▸ | MAP3K11 | Q16584 | 6/20 | 0.51 |
| ▸ | KIT | P10721 | 3/20 | 0.50 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.49 |
| ▸ | AXL | P30530 | 1/20 | 0.49 |
| ▸ | PRKCI | P41743 | 1/20 | 0.49 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.44 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.44 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28598681 | 1.00 | BRD4 (0.66) | BRD4MAP3K11KITLRRK2AXL | |
| SCHEMBL30173296 | 0.83 | KIT (0.48) | BRD4MAP3K11KITAXLPRKCI | |
| SCHEMBL28603783 | 0.83 | KIT (0.48) | BRD4MAP3K11KITAXLPRKCI | |
| SCHEMBL1719183 | 0.80 | BRD4 (1.00) | BRD4LRRK2ACVR1FGFR1 | |
| SCHEMBL28596860 | 0.80 | AXL (0.53) | MAP3K11KITAXLPRKCIFGFR1 | |
| SCHEMBL30173308 | 0.80 | AXL (0.53) | MAP3K11KITAXLPRKCIFGFR1 | |
| SCHEMBL28602125 | 0.79 | PRKCI (0.59) | BRD4LRRK2AXLPRKCIACVR1 | |
| SCHEMBL30173294 | 0.79 | PRKCI (0.59) | BRD4LRRK2AXLPRKCIACVR1 | |
| SCHEMBL1079890 | 0.78 | AXL (0.62) | BRD4KITAXLPRKCIFGFR1 | |
| SCHEMBL30731298 | 0.78 | AXL (0.62) | BRD4KITAXLPRKCIFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113200983-B | Compound with pyrrolopyridine structure, preparation method and medical application | 中国药科大学 | 2023-01-03 | — | — | CN | disclosed |