Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.53 |
| ▸ | PRKCI | P41743 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.47 |
| ▸ | TTBK1 | Q5TCY1 | 2/20 | 0.47 |
| ▸ | TTBK2 | Q6IQ55 | 2/20 | 0.47 |
| ▸ | KIT | P10721 | 3/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | CCNK | O75909 | 1/20 | 0.43 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.43 |
| ▸ | CLK1 | P49759 | 1/20 | 0.42 |
| ▸ | CIT | O14578 | 1/20 | 0.42 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.41 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28596860 | 1.00 | AXL (0.53) | AXLPRKCIMAPK1DYRK1ATTBK1 | |
| SCHEMBL30173316 | 0.84 | AXL (0.61) | AXLPRKCIDYRK1ATTBK1TTBK2 | |
| SCHEMBL28609163 | 0.84 | AXL (0.61) | AXLPRKCIDYRK1ATTBK1TTBK2 | |
| SCHEMBL30173309 | 0.83 | TTBK1 (0.51) | AXLPRKCITTBK1TTBK2KIT | |
| SCHEMBL30173307 | 0.83 | TTBK1 (0.51) | AXLPRKCITTBK1TTBK2KIT | |
| SCHEMBL28596880 | 0.83 | TTBK1 (0.51) | AXLPRKCITTBK1TTBK2KIT | |
| SCHEMBL30173296 | 0.81 | KIT (0.48) | AXLPRKCIDYRK1AKITMAP3K11 | |
| SCHEMBL28598985 | 0.81 | AXL (0.53) | AXLPRKCIMAPK1DYRK1ACLK1 | |
| SCHEMBL30173343 | 0.81 | AXL (0.53) | AXLPRKCIMAPK1DYRK1ACLK1 | |
| SCHEMBL3725709 | 0.80 | JAK2 (0.58) | AXLPRKCIMAPK1DYRK1ATTBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113200983-B | Compound with pyrrolopyridine structure, preparation method and medical application | 中国药科大学 | 2023-01-03 | — | — | CN | disclosed |