Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.51 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.51 |
| ▸ | AXL | P30530 | 1/20 | 0.47 |
| ▸ | PRKCI | P41743 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 5/20 | 0.45 |
| ▸ | BCR | P11274 | 3/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | CDK9 | P50750 | 1/20 | 0.44 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.40 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.40 |
| ▸ | AKT2 | P31751 | 2/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 2/20 | 0.39 |
| ▸ | JAK1 | P23458 | 2/20 | 0.39 |
| ▸ | TYK2 | P29597 | 2/20 | 0.39 |
| ▸ | JAK3 | P52333 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28596880 | 1.00 | TTBK1 (0.51) | TTBK1TTBK2AXLPRKCIABL1 | |
| SCHEMBL30173309 | 1.00 | TTBK1 (0.51) | TTBK1TTBK2AXLPRKCIABL1 | |
| SCHEMBL28596900 | 0.83 | AXL (0.49) | TTBK1AXLPRKCICCNT1CCNA2 | |
| SCHEMBL28596860 | 0.83 | AXL (0.53) | TTBK1TTBK2AXLPRKCIKIT | |
| SCHEMBL30173308 | 0.83 | AXL (0.53) | TTBK1TTBK2AXLPRKCIKIT | |
| SCHEMBL30173331 | 0.83 | AXL (0.49) | TTBK1AXLPRKCICCNT1CCNA2 | |
| SCHEMBL30173343 | 0.81 | AXL (0.53) | AXLPRKCICDK9JAK2JAK3 | |
| SCHEMBL28598985 | 0.81 | AXL (0.53) | AXLPRKCICDK9JAK2JAK3 | |
| SCHEMBL7982849 | 0.81 | ABL1 (0.61) | TTBK1TTBK2PRKCIABL1BCR | |
| SCHEMBL30173316 | 0.79 | AXL (0.61) | TTBK1TTBK2AXLPRKCICDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113200983-B | Compound with pyrrolopyridine structure, preparation method and medical application | 中国药科大学 | 2023-01-03 | — | — | CN | disclosed |