Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MASP2 | O00187 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1690938 | 1.00 | KMT2A (0.54) | KMT2AMEN1NPC1RAB9AGAA | |
| SCHEMBL13804211 | 0.88 | MEN1 (0.50) | KMT2AMEN1NPC1RAB9AGAA | |
| SCHEMBL222446 | 0.87 | RXFP1 (0.55) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL29702265 | 0.87 | RXFP1 (0.55) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL16774987 | 0.81 | GAA (0.52) | KMT2AMEN1NPC1RAB9AGAA | |
| SCHEMBL6852142 | 0.81 | GAA (0.61) | KMT2AMEN1NPC1RAB9AGAA | |
| SCHEMBL1586390 | 0.79 | GAA (0.51) | KMT2AMEN1NPC1RAB9AGAA | |
| SCHEMBL4365913 | 0.79 | GAA (0.53) | KMT2AMEN1NPC1RAB9AGAA | |
| SCHEMBL4371076 | 0.79 | NPC1 (0.51) | KMT2AMEN1NPC1RAB9AGAA | |
| SCHEMBL31738259 | 0.79 | GAA (0.51) | KMT2AMEN1NPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117425476-A | Boric acid compounds, compositions and methods | 塔夫茨大学的受托人 | 2024-01-19 | — | — | CN | disclosed |
| CN-115697413-A | Radiopharmaceuticals and imaging agents targeting FAP and uses related thereto | 塔夫茨大学信托人 | 2023-02-03 | — | — | CN | disclosed |