SCHEMBL29702265

SCHEMBL29702265

CC(C)(C)OC(=O)Nc1ccccc1C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ RXFP1 Q9HBX9 1/20 0.55
▸ KMT2A Q03164 3/20 0.51
▸ MASP2 O00187 1/20 0.51
▸ POLB P06746 2/20 0.51
▸ KDM4E B2RXH2 1/20 0.51
▸ CA12 O43570 2/20 0.50
▸ CA2 P00918 2/20 0.50
▸ CA9 Q16790 2/20 0.50
▸ HCAR2 Q8TDS4 2/20 0.50
▸ LMNA P02545 1/20 0.50
▸ MEN1 O00255 2/20 0.49
▸ PKM P14618 1/20 0.49
▸ DHODH Q02127 2/20 0.48
▸ TRPM8 Q7Z2W7 1/20 0.48
▸ ABCC1 P33527 1/20 0.48
▸ BRD9 Q9H8M2 1/20 0.47
▸ NPC1 O15118 1/20 0.47
▸ RAB9A P51151 1/20 0.47
▸ SMN1; SMN2 Q16637 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL222446 1.00 RXFP1 (0.55) RXFP1KMT2AMASP2POLBKDM4E
SCHEMBL30173444 0.87 KMT2A (0.54) RXFP1KMT2AMASP2POLBKDM4E
SCHEMBL1690938 0.87 KMT2A (0.54) RXFP1KMT2AMASP2POLBKDM4E
SCHEMBL29992092 0.87 RXFP1 (0.59) RXFP1KMT2APOLBLMNAMEN1
SCHEMBL15368377 0.87 RXFP1 (0.59) RXFP1KMT2APOLBLMNAMEN1
SCHEMBL29663621 0.87 RXFP1 (0.55) RXFP1KMT2APOLBKDM4ELMNA
SCHEMBL5812852 0.86 KDM4E (0.51) RXFP1KMT2APOLBKDM4ELMNA
SCHEMBL3248129 0.86 NPC1 (0.54) RXFP1KMT2AKDM4ELMNAMEN1
SCHEMBL2703465 0.86 ALDH1A1 (0.54) RXFP1KMT2APOLBLMNABRD9
SCHEMBL2880191 0.86 LMNA (0.54) RXFP1KMT2APOLBCA12LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118852326-A PROTAC compound for targeted degradation of PI3K 110 beta and preparation method and application thereof 河南大学 2024-10-29 — — CN claimed
CN-122102960-A Synthesis method of nafamostat mesylate — 2026-05-29 — — CN disclosed
CN-121913953-A Preparation method of nafamostat mesylate 鲁南制药集团股份有限公司 2026-04-24 — — CN disclosed
WO-2025081045-A9 CYSTEINE COVALENT MODIFIERS OF AKT1 AND USES THEREOF TERREMOTO BIOSCIENCES, INC. (US) 2025-12-26 — — WO disclosed
CN-116253720-B Pomalidomide linked urea feed additive and preparation method and application thereof 河南湾流生物科技有限公司 2025-09-16 — — CN disclosed
CN-117327052-B 1,2, 3-Triazole feed additive as well as preparation method and application thereof 河南湾流生物科技有限公司 2025-09-16 — — CN disclosed
WO-2025081045-A1 CYSTEINE COVALENT MODIFIERS OF AKT1 AND USES THEREOF TERREMOTO BIOSCIENCES, INC. (US) 2025-04-17 — — WO disclosed
US-20240358735-A1 THERAPEUTIC COMPOSITIONS AND RELATED METHODS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-10-31 — — US disclosed
CN-118852326-A PROTAC compound for targeted degradation of PI3K 110 beta and preparation method and application thereof 河南大学 2024-10-29 — — CN disclosed
EP-4444300-A2 INHIBITORS OF MENIN-MLL INTERACTION Bala Therapeutics, Inc. (US) 2024-10-16 — — EP disclosed
EP-4392037-A1 THERAPEUTIC COMPOSITIONS AND RELATED METHODS Boyce Thompson Institute for Plant Research Inc. (US) 2024-07-03 — — EP disclosed
CN-111867549-B Methods and kits for glycan analysis using blocked 2-AA 安捷伦科技有限公司 2024-01-05 — — CN disclosed
CN-117327052-A 1,2, 3-triazole feed additive as well as preparation method and application thereof 河南湾流生物科技有限公司 2024-01-02 — — CN disclosed
WO-2023107696-A2 INHIBITORS OF MENIN-MLL INTERACTION BALA THERAPEUTICS, INC. (US) 2023-06-15 — — WO disclosed
CN-116253720-A Pomalidomide linked urea feed additive and preparation method and application thereof 河南湾流生物科技有限公司 2023-06-13 — — CN disclosed
WO-2023028350-A1 THERAPEUTIC COMPOSITIONS AND RELATED METHODS BOYCE THOMPSON INSTITUTE FOR PLANT RESEARCH, INC. (US) 2023-03-02 — — WO disclosed
CN-113200885-B Anthranilamide compound based on vorinostat framework, and preparation and application thereof 南华大学 2023-01-06 — — CN disclosed
CN-113185454-B Anthranilic acid amide compound based on entinostat skeleton and preparation and application thereof 南华大学 2022-07-05 — — CN disclosed
US-11376200-B2 Methods and kits for using blocked 2-AA for glycan analysis AGILENT TECHNOLOGIES, INC. 2022-07-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240358735-A1 THERAPEUTIC COMPOSITIONS AND RELATED METHODS MAG, PMP22, B3GAT3 RXFP1 4165/4885KMT2A 3775/4885MASP2 183/4885
US-11376200-B2 Methods and kits for using blocked 2-AA for glycan analysis FUT5, FUT6, B3GNT2 RXFP1 3662/4885KMT2A 649/4885MASP2 62/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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