Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.35 |
| ▸ | CCR9 | P51686 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | GCGR | P47871 | 4/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15527924 | 0.74 | KCNH2 (0.31) | — | |
| SCHEMBL3606688 | 0.72 | GAA (0.55) | EPHX2XDHMEN1NPC1RAB9A | |
| SCHEMBL28023264 | 0.72 | EPHX2 (0.42) | EPHX2XDHMEN1NPC1RAB9A | |
| SCHEMBL20523553 | 0.70 | — | — | |
| SCHEMBL324373 | 0.69 | — | — | |
| SCHEMBL11900195 | 0.69 | EPHX2 (0.44) | EPHX2XDHMEN1NPC1RAB9A | |
| SCHEMBL11901651 | 0.69 | EPHX2 (0.55) | EPHX2XDHMEN1NPC1RAB9A | |
| SCHEMBL597031 | 0.69 | MAPKAPK2 (0.48) | EPHX2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL25777245 | 0.67 | EPHX2 (0.45) | EPHX2XDHMEN1NPC1RAB9A | |
| SCHEMBL27606818 | 0.66 | EPHX2 (0.55) | EPHX2MEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115515591-A | Process for preparing tyrosine receptor kinase inhibitors | 派拉米德生物科学公司 | 2022-12-23 | — | — | CN | disclosed |