Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 10/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | SLC6A7 | Q99884 | 2/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24056629 | 1.00 | RIPK1 (0.41) | RIPK1HTR1ASLC6A7AOC3PARP1 | |
| SCHEMBL25274823 | 1.00 | RIPK1 (0.41) | RIPK1HTR1ASLC6A7AOC3PARP1 | |
| SCHEMBL25274375 | 0.87 | RIPK1 (0.50) | RIPK1HTR1ASLC6A7AOC3PARP1 | |
| SCHEMBL24055263 | 0.87 | RIPK1 (0.50) | RIPK1HTR1ASLC6A7AOC3PARP1 | |
| SCHEMBL24055272 | 0.84 | HTR1A (0.40) | RIPK1HTR1ASLC6A7AOC3PARP1 | |
| SCHEMBL24054009 | 0.84 | RIPK1 (0.38) | RIPK1SLC6A7AOC3PANK3KDR | |
| SCHEMBL25274382 | 0.84 | RIPK1 (0.38) | RIPK1SLC6A7AOC3PANK3KDR | |
| SCHEMBL24055271 | 0.81 | RIPK1 (0.55) | RIPK1 | |
| SCHEMBL25285447 | 0.81 | RIPK1 (0.55) | RIPK1 | |
| SCHEMBL25240594 | 0.81 | RIPK1 (0.50) | RIPK1HTR1AFPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115697972-B | Receptor-interacting protein 1 inhibitors including piperazine heterocyclic amide urea | 维泰瑞隆有限公司 | 2024-11-22 | — | — | CN | disclosed |
| CN-115697972-A | Receptor-interacting protein 1 inhibitors comprising piperazine heterocyclic amide ureas | 维泰瑞隆有限公司 | 2023-02-03 | — | — | CN | disclosed |