Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | SCN4A | P35499 | 9/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SCN1A | P35498 | 2/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13594743 | 0.78 | ADRA2A (0.46) | TSHRSCN4ACYP2D6LMNASCN1A | |
| SCHEMBL516178 | 0.78 | CYP1A2 (0.49) | TSHRSCN4ACYP2D6LMNACYP1A2 | |
| SCHEMBL515979 | 0.76 | SCN4A (0.45) | TSHRSCN4ACYP2D6LMNASCN1A | |
| SCHEMBL11747363 | 0.75 | SCN4A (0.41) | TSHRSCN4ACYP2D6LMNASCN1A | |
| SCHEMBL6272675 | 0.75 | SCN4A (0.50) | TSHRSCN4ACYP2D6LMNASCN1A | |
| SCHEMBL10604452 | 0.73 | CYP3A4 (0.41) | TSHRCYP2D6LMNACYP1A2CYP3A4 | |
| SCHEMBL3402150 | 0.73 | SCN4A (0.46) | TSHRSCN4ACYP2D6LMNASCN1A | |
| SCHEMBL3400237 | 0.73 | SCN4A (0.45) | TSHRSCN4ACYP2D6LMNASCN1A | |
| SCHEMBL8935675 | 0.73 | SMN1; SMN2 (0.58) | KMT2AHPGDSMN1; SMN2L3MBTL1CXCR5 | |
| SCHEMBL8935678 | 0.73 | SMN1; SMN2 (0.58) | KMT2AHPGDSMN1; SMN2L3MBTL1CXCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119118953-A | Charged ion channel blockers and methods of use thereof | 诺西恩医疗公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-115279731-B | Charged ion channel blockers and methods of use thereof | 诺西恩医疗公司 | 2024-09-13 | — | — | CN | disclosed |
| CN-115279731-A | Charged ion channel blockers and methods of use thereof | 诺西恩医疗公司 | 2022-11-01 | — | — | CN | disclosed |