Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.63 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 3/20 | 0.44 |
| ▸ | ALKBH2 | Q6NS38 | 2/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | FADS1 | O60427 | 2/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 6/20 | 0.36 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30209662 | 0.85 | L3MBTL1 (0.45) | L3MBTL1ROCK1ACHEFADS1SCD5 | |
| SCHEMBL2148413 | 0.83 | L3MBTL1 (0.57) | L3MBTL1ROCK1ACHEALKBH2HPGDS | |
| SCHEMBL12804394 | 0.81 | L3MBTL1 (0.69) | L3MBTL1ACHEALKBH2HPGDSCYP4F2 | |
| SCHEMBL23989708 | 0.80 | L3MBTL1 (0.58) | L3MBTL1ACHEALKBH2HPGDSCYP4F2 | |
| SCHEMBL18038382 | 0.79 | L3MBTL1 (0.71) | L3MBTL1ACHEALKBH2HPGDSCYP4F2 | |
| SCHEMBL5732657 | 0.77 | L3MBTL1 (0.69) | L3MBTL1ACHEALKBH2HPGDSCYP4F2 | |
| SCHEMBL27716505 | 0.77 | L3MBTL1 (0.69) | L3MBTL1ACHEALKBH2HPGDSCYP4F2 | |
| SCHEMBL4240582 | 0.77 | L3MBTL1 (1.00) | L3MBTL1ACHEALKBH2HPGDSCYP4F2 | |
| SCHEMBL4022892 | 0.77 | L3MBTL1 (0.62) | L3MBTL1ACHEALKBH2HPGDSCYP4F2 | |
| SCHEMBL31681673 | 0.76 | L3MBTL1 (0.67) | L3MBTL1ACHEALKBH2HPGDSCYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4408530-A1 | BENZIMIDAZOLES AS MODULATORS OF IL-17 | Janssen Pharmaceutica NV (BE) | 2024-08-07 | — | — | EP | disclosed |
| WO-2023049888-A1 | BENZIMIDAZOLES AS MODULATORS OF IL-17 | JANSSEN PHARMACEUTICA NV (BE) | 2023-03-30 | — | — | WO | disclosed |
| CN-115867348-A | Imidazopyrimidines as IL-17 modulators | 詹森药业有限公司 | 2023-03-28 | — | — | CN | disclosed |
| EP-4143195-A1 | IMIDAZOPYRIDAZINES AS MODULATORS OF IL-17 | Janssen Pharmaceutica NV (BE) | 2023-03-08 | — | — | EP | disclosed |
| EP-4143193-A1 | IMIDAZOPYRIMIDINES AS MODULATORS OF IL-17 | JANSSEN Pharmaceutica NV (BE) | 2023-03-08 | — | — | EP | disclosed |