Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | BRAF | P15056 | 4/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 2/20 | 0.32 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23782471 | 1.00 | NPC1 (0.37) | NPC1LMNAPOLBRAB9ATRPV4 | |
| SCHEMBL23782347 | 0.92 | TRPV4 (0.37) | NPC1LMNAPOLBRAB9ATRPV4 | |
| SCHEMBL23782516 | 0.90 | TEAD2 (0.37) | NPC1LMNAPOLBRAB9APTGDR2 | |
| SCHEMBL30173731 | 0.90 | TEAD2 (0.37) | NPC1LMNAPOLBRAB9APTGDR2 | |
| SCHEMBL23792708 | 0.85 | PTGDR2 (0.45) | NPC1LMNAPOLBRAB9APTGDR2 | |
| SCHEMBL23792710 | 0.84 | PTGDR2 (0.44) | NPC1LMNAPOLBRAB9APTGDR2 | |
| SCHEMBL23782532 | 0.83 | POLB (0.42) | NPC1LMNAPOLBRAB9APTGDR2 | |
| SCHEMBL23792441 | 0.82 | LMNA (0.38) | NPC1LMNAPOLBRAB9APTGDR2 | |
| SCHEMBL26240315 | 0.82 | NPC1 (0.38) | NPC1LMNAPOLBRAB9APTGDR2 | |
| SCHEMBL23782543 | 0.82 | TEAD2 (0.40) | NPC1LMNAPOLBRAB9APTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115515685-B | EIF4E inhibitors and uses thereof | 皮克医疗公司 | 2025-04-08 | — | — | CN | disclosed |
| EP-4114529-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. (US) | 2023-01-11 | — | — | EP | disclosed |
| CN-115515685-A | EIF4E inhibitor and application thereof | 皮克医疗公司 | 2022-12-23 | — | — | CN | disclosed |