Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | RORB | Q92753 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23782583 | 1.00 | DHODH (0.49) | DHODHMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL30173780 | 0.93 | DHODH (0.47) | DHODHMAPTRORBPOLBKMT2A | |
| SCHEMBL23782602 | 0.93 | DHODH (0.47) | DHODHMAPTRORBPOLBKMT2A | |
| SCHEMBL26241852 | 0.88 | MAPT (0.48) | DHODHMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL23791820 | 0.88 | DHODH (0.46) | DHODHMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL23782503 | 0.87 | NOTUM (0.44) | DHODHKDM4ELMNATP53RORB | |
| SCHEMBL30176220 | 0.87 | NOTUM (0.44) | DHODHKDM4ELMNATP53RORB | |
| SCHEMBL26242452 | 0.83 | PTPN1 (0.39) | DHODHMAPTPOLBKMT2A | |
| SCHEMBL23791737 | 0.82 | IGF2BP2 (0.46) | DHODHMAPTTP53 | |
| SCHEMBL26241850 | 0.80 | PTPN1 (0.41) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115515685-B | EIF4E inhibitors and uses thereof | 皮克医疗公司 | 2025-04-08 | — | — | CN | disclosed |
| EP-4114529-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. (US) | 2023-01-11 | — | — | EP | disclosed |
| CN-115515685-A | EIF4E inhibitor and application thereof | 皮克医疗公司 | 2022-12-23 | — | — | CN | disclosed |