Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.47 |
| ▸ | RORB | Q92753 | 2/20 | 0.42 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.39 |
| ▸ | PTPRF | P10586 | 1/20 | 0.39 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | PTPRA | P18433 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23782602 | 1.00 | DHODH (0.47) | DHODHRORBIGF2BP2PTPN1PTPRF | |
| SCHEMBL30173735 | 0.93 | DHODH (0.49) | DHODHRORBPOLBMAPTKMT2A | |
| SCHEMBL23782583 | 0.93 | DHODH (0.49) | DHODHRORBPOLBMAPTKMT2A | |
| SCHEMBL26242452 | 0.90 | PTPN1 (0.39) | DHODHPTPN1PTPRFRORCMEN1 | |
| SCHEMBL23791737 | 0.89 | IGF2BP2 (0.46) | DHODHIGF2BP2PTPN1PTPRFRORC | |
| SCHEMBL26241850 | 0.88 | PTPN1 (0.41) | DHODHIGF2BP2PTPN1PTPRFRORC | |
| SCHEMBL26242454 | 0.86 | DHODH (0.45) | DHODHIGF2BP2PTPN1PTPRFRORC | |
| SCHEMBL23782401 | 0.82 | DHODH (0.45) | DHODHRORBRAPGEF3RAPGEF4RORC | |
| SCHEMBL30173772 | 0.82 | DHODH (0.45) | DHODHRORBRAPGEF3RAPGEF4RORC | |
| SCHEMBL23791736 | 0.82 | DHODH (0.47) | DHODHRORBRORCMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115515685-B | EIF4E inhibitors and uses thereof | 皮克医疗公司 | 2025-04-08 | — | — | CN | disclosed |
| EP-4114529-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. (US) | 2023-01-11 | — | — | EP | disclosed |
| CN-115515685-A | EIF4E inhibitor and application thereof | 皮克医疗公司 | 2022-12-23 | — | — | CN | disclosed |