Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.45 |
| ▸ | RORB | Q92753 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 4/20 | 0.36 |
| ▸ | BCR | P11274 | 4/20 | 0.36 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | TEK | Q02763 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23782401 | 1.00 | DHODH (0.45) | DHODHRORBKDRSYKABL1 | |
| SCHEMBL23792008 | 0.90 | DHODH (0.39) | DHODHRORBKDRABL1BCR | |
| SCHEMBL23782375 | 0.89 | DHODH (0.41) | DHODHRORC | |
| SCHEMBL23792005 | 0.89 | DHODH (0.43) | DHODHRORBKDRRORCNOTUM | |
| SCHEMBL26242060 | 0.88 | DHODH (0.40) | DHODHABL1RORC | |
| SCHEMBL23791998 | 0.87 | DHODH (0.46) | DHODHRORBKDRNOTUMKDM2B | |
| SCHEMBL23792007 | 0.84 | KMO (0.39) | DHODHKDRSYK | |
| SCHEMBL23782602 | 0.82 | DHODH (0.47) | DHODHRORBRAPGEF3RAPGEF4RORC | |
| SCHEMBL30173780 | 0.82 | DHODH (0.47) | DHODHRORBRAPGEF3RAPGEF4RORC | |
| SCHEMBL23782403 | 0.81 | NOTUM (0.43) | DHODHRORBKDRRAPGEF3RAPGEF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115515685-B | EIF4E inhibitors and uses thereof | 皮克医疗公司 | 2025-04-08 | — | — | CN | disclosed |
| EP-4114529-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. (US) | 2023-01-11 | — | — | EP | disclosed |
| CN-115515685-A | EIF4E inhibitor and application thereof | 皮克医疗公司 | 2022-12-23 | — | — | CN | disclosed |