Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 2/20 | 0.47 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | EIF4E | P06730 | 1/20 | 0.38 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23782529 | 1.00 | GRN (0.47) | GRNSORT1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL23792010 | 0.92 | GRN (0.45) | GRNSORT1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL23792013 | 0.90 | GRN (0.41) | GRNSORT1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL26240299 | 0.89 | GRN (0.40) | GRNSORT1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL23792017 | 0.89 | MEN1 (0.41) | GRNSORT1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL23792000 | 0.89 | FPR2 (0.45) | GRNSORT1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL23792015 | 0.88 | GRN (0.40) | GRNSORT1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL23792019 | 0.86 | GRN (0.38) | GRNSORT1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL23791772 | 0.86 | PTGDR2 (0.46) | GRNSORT1MEN1KMT2APTGDR2 | |
| SCHEMBL23782502 | 0.85 | CTSK (0.42) | PTGDR2DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115515685-B | EIF4E inhibitors and uses thereof | 皮克医疗公司 | 2025-04-08 | — | — | CN | disclosed |
| CN-115515685-A | EIF4E inhibitor and application thereof | 皮克医疗公司 | 2022-12-23 | — | — | CN | disclosed |