Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.56 |
| ▸ | FEN1 | P39748 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 4/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2258001 | 1.00 | ALDH1A1 (0.62) | ALDH1A1MAPK1HIF1AERCC5FEN1 | |
| SCHEMBL23792637 | 0.85 | ALDH1A1 (0.57) | ALDH1A1MAPK1HIF1AERCC5FEN1 | |
| SCHEMBL3182336 | 0.83 | KDM4E (0.47) | ALDH1A1MAPK1HIF1ATSHRKDM4E | |
| SCHEMBL28019534 | 0.81 | ALDH1A1 (0.49) | ALDH1A1MAPK1HIF1AMAPTKDM4E | |
| SCHEMBL5272634 | 0.80 | ALDH1A1 (0.56) | ALDH1A1MAPK1HIF1AERCC5FEN1 | |
| SCHEMBL1144066 | 0.79 | ALDH1A1 (0.69) | ALDH1A1MAPK1HIF1AERCC5FEN1 | |
| SCHEMBL29712843 | 0.79 | ALDH1A1 (0.69) | ALDH1A1MAPK1HIF1AERCC5FEN1 | |
| SCHEMBL10825956 | 0.79 | ALDH1A1 (0.59) | ALDH1A1MAPK1HIF1AERCC5FEN1 | |
| SCHEMBL10788696 | 0.78 | ALDH1A1 (0.57) | ALDH1A1MAPK1HIF1AERCC5FEN1 | |
| SCHEMBL11650545 | 0.78 | ERCC5 (0.53) | ALDH1A1ERCC5FEN1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115515685-B | EIF4E inhibitors and uses thereof | 皮克医疗公司 | 2025-04-08 | — | — | CN | disclosed |
| CN-115515685-A | EIF4E inhibitor and application thereof | 皮克医疗公司 | 2022-12-23 | — | — | CN | disclosed |