Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.53 |
| ▸ | FEN1 | P39748 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.44 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12237061 | 0.80 | ERCC5 (0.45) | ERCC5FEN1CES2CES1ALDH1A1 | |
| SCHEMBL19984929 | 0.79 | ERCC5 (0.51) | ERCC5FEN1CES2CES1ALDH1A1 | |
| SCHEMBL27925176 | 0.78 | FFAR1 (0.48) | ALDH1A1RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL13647199 | 0.78 | ERCC5 (0.55) | ERCC5FEN1ALDH1A1RAB9AMEN1 | |
| SCHEMBL8635130 | 0.78 | ALDH1A1 (0.44) | ALDH1A1RAB9AKDM4ELMNASMN1; SMN2 | |
| SCHEMBL13257558 | 0.78 | ALDH1A1 (0.56) | ALDH1A1KDM4EMAPTSMN1; SMN2HPGD | |
| SCHEMBL30173802 | 0.78 | ALDH1A1 (0.62) | ERCC5FEN1ALDH1A1RECQLRAB9A | |
| SCHEMBL2258001 | 0.78 | ALDH1A1 (0.62) | ERCC5FEN1ALDH1A1RECQLRAB9A | |
| SCHEMBL2837238 | 0.78 | ERCC5 (0.58) | ERCC5FEN1CES2CES1ALDH1A1 | |
| SCHEMBL15979733 | 0.77 | CES2 (0.62) | ERCC5FEN1CES2CES1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024112694-A1 | RECOMBINANT POLYPEPTIDES WITH PRENYLTRANSFERASE ACTIVITY FOR BIOSYNTHESIS OF CANNABINOIDS AND HOP COMPOUNDS | WILLOW BIOSCIENCES, INC. (CA) | 2024-05-30 | — | — | WO | claimed |
| CN-109415681-A | For producing the composition and method of type III polyketone in oleaginous yeast kind | 德克萨斯大学系统董事会 | 2019-03-01 | — | — | CN | claimed |
| EP-3430124-A1 | COMPOSITIONS AND METHODS FOR TYPE III POLYKETIDE PRODUCTION IN OLEAGINOUS YEAST SPECIES | Board of Regents, The University of Texas System (US) | 2019-01-23 | — | — | EP | claimed |
| WO-2017160801-A1 | COMPOSITIONS AND METHODS FOR TYPE III POLYKETIDE PRODUCTION IN OLEAGINOUS YEAST SPECIES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-09-21 | — | — | WO | claimed |
| WO-2024112694-A1 | RECOMBINANT POLYPEPTIDES WITH PRENYLTRANSFERASE ACTIVITY FOR BIOSYNTHESIS OF CANNABINOIDS AND HOP COMPOUNDS | WILLOW BIOSCIENCES, INC. (CA) | 2024-05-30 | — | — | WO | disclosed |
| US-20240043850-A1 | COMPOSITIONS AND METHODS FOR TYPE III POLYKETIDE PRODUCTION IN OLEAGINOUS YEAST SPECIES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2024-02-08 | — | — | US | disclosed |
| US-11820987-B2 | Compositions and methods for type III polyketide production in oleaginous yeast species | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-11-21 | — | — | US | disclosed |
| US-20190078098-A1 | COMPOSITIONS AND METHODS FOR TYPE III POLYKETIDE PRODUCTION IN OLEAGINOUS YEAST SPECIES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2019-03-14 | — | — | US | disclosed |
| CN-109415681-A | For producing the composition and method of type III polyketone in oleaginous yeast kind | 德克萨斯大学系统董事会 | 2019-03-01 | — | — | CN | disclosed |
| EP-3430124-A1 | COMPOSITIONS AND METHODS FOR TYPE III POLYKETIDE PRODUCTION IN OLEAGINOUS YEAST SPECIES | Board of Regents, The University of Texas System (US) | 2019-01-23 | — | — | EP | disclosed |
| US-20180312887-A1 | MICROBIAL PRODUCTION OF CHEMICAL PRODUCTS AND RELATED COMPOSITIONS, METHODS AND SYSTEMS | CARGILL INC (US) | 2018-11-01 | — | — | US | disclosed |
| US-20180312886-A1 | MICROBIAL PRODUCTION OF CHEMICAL PRODUCTS AND RELATED COMPOSITIONS, METHODS AND SYSTEMS | CARGILL INC (US) | 2018-11-01 | — | — | US | disclosed |
| US-20090192129-A1 | BICYCLIC PYRROLE DERIVATIVES | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2009-07-30 | — | — | US | disclosed |
| US-20090149483-A1 | BICYCLIC PYRROLE DERIVATIVES | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2009-06-11 | — | — | US | disclosed |
| US-20080318922-A1 | Bicyclic Pyrrole Derivatives | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2008-12-25 | — | — | US | disclosed |
| EP-1829877-A1 | BICYCLIC PYRROLE DERIVATIVES | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2007-09-05 | — | — | EP | disclosed |
| US-20070105890-A1 | Novel condensed imidazole derivative | DAINIPPON SUMITOMO PHARMA CO., LTD | 2007-05-10 | — | — | US | disclosed |
| US-20070082908-A1 | Bicycle pyrazole derivative | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-04-12 | — | — | US | disclosed |
| US-20070082908-A1 | Bicycle pyrazole derivative | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-04-12 | — | — | US | disclosed |
| US-4101585-A | PRENYLATION OF ACYLPHLOROGLUCINOLS | CIBA-GEIGY CORPORATION (US) | 1978-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105890-A1 | Novel condensed imidazole derivative | DPP4, DPP7, DPP3 | ERCC5 4609/4885FEN1 3647/4885CES2 432/4885 |
| US-20080318922-A1 | Bicyclic Pyrrole Derivatives | DPP4, DPP7, DPP3 | ERCC5 4576/4885FEN1 2504/4885CES2 127/4885 |
| US-20090192129-A1 | BICYCLIC PYRROLE DERIVATIVES | DPP4, DPP7, DPP3 | ERCC5 4672/4885FEN1 2384/4885CES2 170/4885 |
| US-20090149483-A1 | BICYCLIC PYRROLE DERIVATIVES | DPP4, DPP7, DPP3 | ERCC5 4672/4885FEN1 2384/4885CES2 170/4885 |
| US-20070082908-A1 | Bicycle pyrazole derivative | DPP4, DPP7, DPP3 | ERCC5 4293/4885FEN1 3989/4885CES2 436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.