Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | KIT | P10721 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | QPCT | Q16769 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 4/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1976134 | 0.83 | FLT3 (0.76) | FLT3MAPTPOLBMEN1KMT2A | |
| SCHEMBL30174079 | 0.81 | TUBB4A (0.50) | MAPTPOLBMEN1KMT2AADORA3 | |
| SCHEMBL29074005 | 0.80 | ABCB1 (0.65) | FLT3MAPTMEN1KMT2AKDM4E | |
| SCHEMBL30577294 | 0.80 | ABCB1 (0.65) | FLT3MAPTMEN1KMT2AKDM4E | |
| SCHEMBL23383379 | 0.78 | MAPT (0.64) | FLT3MAPTPOLBMEN1KMT2A | |
| SCHEMBL15245959 | 0.77 | FLT3 (0.74) | FLT3MAPTPOLBMEN1KMT2A | |
| SCHEMBL30577296 | 0.77 | CREB1 (0.69) | FLT3MAPTPOLBMEN1KMT2A | |
| SCHEMBL29149099 | 0.77 | ABCB1 (0.61) | FLT3MAPTPOLBMEN1KMT2A | |
| SCHEMBL29074013 | 0.77 | CREB1 (0.69) | FLT3MAPTPOLBMEN1KMT2A | |
| SCHEMBL30730485 | 0.77 | ABCB1 (0.61) | FLT3MAPTPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4367121-A1 | COMPOUND OF THE 7A,8,9,10,11,11A-HEXAHYDRO-1H,7H-PYRANO[2,3-C]XANTHENE TYPE, METHOD OF PREPARATION THEREOF, INTERMEDIATES THEREOF AND THERAPEUTIC APPLICATIONS THEREOF | Centre National de la Recherche Scientifique (FR) | 2024-05-15 | — | — | EP | claimed |
| WO-2023280746-A1 | COMPOUND OF THE 7A,8,9,10,11,11A-HEXAHYDRO-1H,7H-PYRANO[2,3-C]XANTHENE TYPE, METHOD OF PREPARATION THEREOF, INTERMEDIATES THEREOF AND THERAPEUTIC APPLICATIONS THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2023-01-12 | — | — | WO | claimed |
| US-20240425515-A1 | COMPOUND OF THE 7A,8,9,10,11,11A-HEXAHYDRO-1H,7H-PYRANO[2,3-C]XANTHENE TYPE, METHOD OF PREPARATION THEREOF, INTERMEDIATES THEREOF AND THERAPEUTIC APPLICATIONS THEREOF | CENTRE NAT RECH SCIENT (FR) | 2024-12-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240425515-A1 | COMPOUND OF THE 7A,8,9,10,11,11A-HEXAHYDRO-1H,7H-PYRANO[2,3-C]XANTHENE TYPE, METHOD OF PREPARATION THEREOF, INTERMEDIATES THEREOF AND THERAPEUTIC APPLICATIONS THEREOF | HK1, HK2, C1R | FLT3 3325/4885MAPT 4606/4885POLB 3170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.