Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30174315 | 0.83 | ELANE (0.37) | NR4A2L3MBTL1TDP1POLBCTDSP1 | |
| SCHEMBL30174300 | 0.77 | L3MBTL1 (0.39) | L3MBTL1TDP1POLBCTDSP1KDM4E | |
| Hydrochloric Acid SCHEMBL29812500 | 0.76 | KDM4E (0.41) | L3MBTL1POLBKDM4EMAPTKMT2A | |
| SCHEMBL18920575 | 0.75 | KEAP1 (0.44) | L3MBTL1TDP1POLBCTDSP1KDM4E | |
| SCHEMBL29811076 | 0.72 | MAP2K1 (0.40) | TDP1POLBKDM4EALDH1A1HPGD | |
| SCHEMBL30174175 | 0.72 | L3MBTL1 (0.41) | L3MBTL1TDP1POLBCTDSP1KDM4E | |
| SCHEMBL25529106 | 0.70 | L3MBTL1 (0.44) | L3MBTL1TDP1POLBCTDSP1KDM4E | |
| Hydrochloric Acid SCHEMBL29812328 | 0.70 | MAP4K4 (0.39) | KDM4ETGFBR1 | |
| SCHEMBL28199979 | 0.70 | KDM4E (0.38) | L3MBTL1TDP1POLBKDM4E | |
| SCHEMBL29811081 | 0.68 | MAP2K1 (0.39) | KDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605478-A | Compounds and methods of use | 埃克塞里艾克西斯公司（US） | 2023-01-13 | — | — | CN | disclosed |