Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 1/20 | 0.50 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29465809 | 0.90 | MTNR1A (0.47) | PLA2G4AMTNR1AMTNR1BMAPTLMNA | |
| SCHEMBL25998805 | 0.89 | SIRT2 (0.49) | PLA2G4AHPGDMAPTLMNANR1I2 | |
| SCHEMBL17103068 | 0.89 | BRD4 (0.48) | HPGDMTNR1AMTNR1BMAPTLMNA | |
| SCHEMBL1539106 | 0.89 | HPGD (0.60) | PLA2G4ATLR8HPGDMAPTLMNA | |
| SCHEMBL2935051 | 0.86 | MTNR1A (0.48) | HPGDMTNR1AMTNR1BMAPTLMNA | |
| SCHEMBL25998809 | 0.85 | SMPD1 (0.48) | PLA2G4AHPGDMAPTLMNANR1I2 | |
| SCHEMBL17263071 | 0.85 | MTNR1A (0.51) | MTNR1AMTNR1BMAPTLMNABRD4 | |
| SCHEMBL17263019 | 0.84 | KDM4E (0.51) | MTNR1AMTNR1BMAPTLMNABRD4 | |
| SCHEMBL28754371 | 0.84 | KMT2A (0.55) | HPGDMTNR1AMTNR1BMAPTLMNA | |
| SCHEMBL29737945 | 0.84 | KMT2A (0.55) | HPGDMTNR1AMTNR1BMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115515956-A | Benzimidazole derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2022-12-23 | — | — | CN | disclosed |