Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30174389 | 0.90 | PLA2G4A (0.50) | MTNR1AMTNR1BBRD4FGFR1POLB | |
| SCHEMBL17263071 | 0.90 | MTNR1A (0.51) | MTNR1AMTNR1BBRD4FGFR1POLB | |
| SCHEMBL17103068 | 0.89 | BRD4 (0.48) | MTNR1AMTNR1BBRD4FGFR1POLB | |
| SCHEMBL2935051 | 0.86 | MTNR1A (0.48) | MTNR1AMTNR1BBRD4FGFR1POLB | |
| SCHEMBL29649186 | 0.85 | FGFR1 (0.50) | MTNR1AMTNR1BFGFR1MAPTHDAC1 | |
| SCHEMBL29737945 | 0.84 | KMT2A (0.55) | MTNR1AMTNR1BBRD4FGFR1POLB | |
| SCHEMBL28754371 | 0.84 | KMT2A (0.55) | MTNR1AMTNR1BBRD4FGFR1POLB | |
| SCHEMBL17263019 | 0.82 | KDM4E (0.51) | MTNR1AMTNR1BBRD4FGFR1POLB | |
| SCHEMBL16406499 | 0.80 | MTNR1A (0.60) | MTNR1AMTNR1BBRD4MAPTMAPK1 | |
| SCHEMBL1307034 | 0.80 | FGFR1 (0.57) | MTNR1AMTNR1BBRD4FGFR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057771-A | Macrocyclic compound and preparation method and application thereof | 北京鞍石生物科技有限责任公司 | 2022-02-18 | — | — | CN | disclosed |