Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 13/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23930066 | 1.00 | KCNJ1 (0.57) | KCNJ1LMNAKDM4EALDH1A1RXFP1 | |
| SCHEMBL14822074 | 0.88 | LMNA (0.57) | LMNAEGLN1ALKBH2 | |
| SCHEMBL17966640 | 0.83 | KCNJ1 (0.56) | KCNJ1LMNAKDM4EALDH1A1EGLN1 | |
| SCHEMBL23957800 | 0.83 | KCNJ1 (0.56) | KCNJ1LMNAEGLN1KMT2A | |
| SCHEMBL29520978 | 0.83 | KCNJ1 (0.56) | KCNJ1LMNAKDM4EALDH1A1EGLN1 | |
| SCHEMBL16547509 | 0.78 | ALDH1A1 (0.44) | KDM4EALDH1A1EGLN1KMT2AMAPT | |
| SCHEMBL24668346 | 0.75 | MAPT (0.64) | KCNJ1LMNAKDM4EALDH1A1RXFP1 | |
| SCHEMBL3358360 | 0.75 | KCNJ1 (0.61) | KCNJ1LMNAKDM4EALDH1A1EGLN1 | |
| SCHEMBL3503653 | 0.75 | LMNA (0.75) | KCNJ1LMNAKDM4EALDH1A1RXFP1 | |
| SCHEMBL30175326 | 0.75 | LMNA (0.75) | KCNJ1LMNAKDM4EALDH1A1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605477-B | Pyrazolo [1,5-a ] pyridine derivative, preparation method, composition and application thereof | 深圳众格生物科技有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-115605477-A | Pyrazolo [1,5-a ] pyridine derivative and preparation method, composition and application thereof | 深圳众格生物科技有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |