SCHEMBL30175321

SCHEMBL30175321

CCC(=O)c1ccc(Cl)nc1

nearest known ligand 0.60

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NAPRT Q6XQN6 1/20 0.60
RAB9A P51151 6/20 0.55
L3MBTL1 Q9Y468 3/20 0.55
MAPT P10636 2/20 0.55
DGAT1 O75907 2/20 0.54
GRM4 Q14833 4/20 0.51
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
ALDH1A1 P00352 2/20 0.50
LMNA P02545 1/20 0.50
PKM P14618 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
POLB P06746 2/20 0.48
GAA P10253 1/20 0.47
NPC1 O15118 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1877325 1.00 NAPRT (0.60) NAPRTRAB9AL3MBTL1MAPTDGAT1
SCHEMBL27417479 0.86 MAPT (0.56) NAPRTRAB9AL3MBTL1MAPTDGAT1
SCHEMBL11899972 0.85 NAPRT (0.56) NAPRTRAB9AL3MBTL1MAPTDGAT1
SCHEMBL1985578 0.84 NAPRT (0.64) NAPRTRAB9AL3MBTL1MAPTDGAT1
SCHEMBL6439911 0.82 NAPRT (0.62) NAPRTRAB9AL3MBTL1MAPTDGAT1
SCHEMBL4899048 0.82 NAPRT (0.62) NAPRTRAB9AL3MBTL1MAPTDGAT1
SCHEMBL20372049 0.82 HSD17B3 (0.54) NAPRTRAB9AL3MBTL1MAPTDGAT1
SCHEMBL3464701 0.81 NAPRT (0.56) NAPRTRAB9AL3MBTL1MAPTDGAT1
SCHEMBL2271956 0.81 HSD17B3 (0.56) NAPRTRAB9AL3MBTL1MAPTDGAT1
Hydrochloric Acid SCHEMBL4894083 0.81 NAPRT (0.60) NAPRTRAB9AL3MBTL1MAPTDGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025090578-A1 HETEROCYCLIC HYDRAZONES AS NEMATICIDES FMC CORPORATION (US) 2025-05-01 WO disclosed
CN-115605477-B Pyrazolo [1,5-a ] pyridine derivative, preparation method, composition and application thereof 深圳众格生物科技有限公司 2024-07-05 CN disclosed
CN-115605477-A Pyrazolo [1,5-a ] pyridine derivative and preparation method, composition and application thereof 深圳众格生物科技有限公司(CN) 2023-01-13 CN disclosed