SCHEMBL30175807

CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(OC(C)(C)C)cc1)NC(=O)[C@H](COC(C)(C)C)NC(=O)[C@H](COC(C)(C)C)NC(=O)[C@@H](NC(=O)[C@H](CC(=O)OC(C)(C)C)NC(=O)[C@H](COC(C)(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1)NC(=O)OC(C)(C)C)[C@@H](C)OC(C)(C)C)[C@@H](C)OC(C)(C)C)C(C)C)C(=O)N[C@@H](CCC(=O)OC(C)(C)C)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	REN	P00797	5/20	0.39

▸	OPRM1	P35372	7/20	0.38

▸	OPRD1	P41143	7/20	0.38

▸	OPRK1	P41145	7/20	0.38

▸	TFPI	P10646	1/20	0.38

▸	GLP1R	P43220	2/20	0.38

▸	SCTR	P47872	1/20	0.38

▸	BACE1	P56817	4/20	0.37

▸	BACE2	Q9Y5Z0	1/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30175817	0.94	OPRM1 (0.40)	OPRM1OPRD1OPRK1TFPIGLP1R
SCHEMBL34461945	0.92	REN (0.40)	RENOPRD1BACE1
SCHEMBL30884234	0.91	OPRM1 (0.44)	OPRM1OPRD1OPRK1GLP1RSCTR
SCHEMBL30437059	0.91	REN (0.39)	RENOPRD1BACE1
SCHEMBL31175849	0.91	OPRM1 (0.39)	OPRM1OPRD1OPRK1GLP1RSCTR
SCHEMBL34461946	0.90	REN (0.39)	RENOPRD1
SCHEMBL31255808	0.90	OPRM1 (0.43)	OPRM1OPRD1OPRK1GLP1RSCTR
SCHEMBL30836835	0.89	OPRM1 (0.40)	OPRM1OPRD1OPRK1TFPIGLP1R
SCHEMBL31210152	0.88	PSMB8 (0.37)	RENOPRM1OPRD1OPRK1GLP1R
SCHEMBL31567827	0.88	GLP1R (0.44)	OPRM1OPRD1OPRK1GLP1RSCTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-110845600-B	Method for preparing liraglutide	鲁南制药集团股份有限公司	2022-12-27	—	—	CN	claimed