Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 20/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1563785 | 0.97 | BDKRB2 (0.85) | BDKRB2 | |
| SCHEMBL13145062 | 0.89 | BDKRB2 (1.00) | BDKRB2 | |
| SCHEMBL1564657 | 0.87 | BDKRB2 (0.58) | BDKRB2 | |
| SCHEMBL13145080 | 0.79 | BDKRB2 (0.78) | BDKRB2 | |
| SCHEMBL13145033 | 0.79 | BDKRB2 (0.79) | BDKRB2 | |
| SCHEMBL13145081 | 0.78 | BDKRB2 (0.77) | BDKRB2 | |
| SCHEMBL13145088 | 0.78 | BDKRB2 (0.77) | BDKRB2 | |
| SCHEMBL13145108 | 0.75 | BDKRB2 (0.73) | BDKRB2 | |
| SCHEMBL1563888 | 0.74 | BDKRB2 (1.00) | BDKRB2 | |
| SCHEMBL13145015 | 0.74 | BDKRB2 (1.00) | BDKRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2144897-A1 | 8-OXY-QUINOLINE DERIVATIVES AS BRADYKININ B2 RECEPTOR MODULATORS | Jerini AG (DE) | 2010-01-20 | — | — | EP | disclosed |
| WO-2008116620-A1 | 8-OXY-QUINOLINE DERIVATIVES AS BRADYKININ B2 RECEPTOR MODULATORS | JERINI AG (DE) | 2008-10-02 | — | — | WO | disclosed |