Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.45 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GRM1 | Q13255 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12335152 | 0.80 | SMN1; SMN2 (0.57) | TSHRSMN1; SMN2NPC1MAPTRAB9A | |
| SCHEMBL13740923 | 0.77 | CYP2A6 (0.44) | TSHRSMN1; SMN2NPC1MAPTRAB9A | |
| SCHEMBL18949738 | 0.77 | TSHR (0.49) | TSHRSMN1; SMN2NPC1MAPTRAB9A | |
| SCHEMBL30828481 | 0.76 | CCNA2 (0.44) | CCNA2CDK2CCNA1F7F3 | |
| SCHEMBL30140734 | 0.71 | NPC1 (0.46) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL30235475 | 0.70 | F7 (0.47) | CCNA2CDK2CCNA1F7F3 | |
| SCHEMBL2689254 | 0.69 | SMN1; SMN2 (0.45) | SMN1; SMN2NPC1MAPTRAB9AGRM1 | |
| SCHEMBL1680449 | 0.69 | POLB (0.56) | NPC1RAB9AGRM1CYP1A2CYP2C19 | |
| SCHEMBL25823001 | 0.68 | CYP2A6 (0.44) | TSHRSMN1; SMN2NPC1MAPTRAB9A | |
| SCHEMBL15768639 | 0.68 | CYP2A6 (0.44) | SMN1; SMN2NPC1MAPTRAB9AGRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4143168-A1 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS | Plexxikon Inc. (US) | 2023-03-08 | — | — | EP | disclosed |
| CN-115605460-A | Synthesis of heterocyclic compounds | 普莱希科公司（US） | 2023-01-13 | — | — | CN | disclosed |