Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.44 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.40 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18949738 | 0.83 | TSHR (0.49) | CYP2A6CYP2E1CYP3A4SMN1; SMN2GRM1 | |
| SCHEMBL12335152 | 0.77 | SMN1; SMN2 (0.57) | CYP2A6CYP2E1CYP3A4PIK3CDSMN1; SMN2 | |
| SCHEMBL18131331 | 0.75 | PIK3CD (0.51) | PIK3CDPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL2689168 | 0.75 | CYP2A6 (0.45) | CYP2A6CYP2E1CYP3A4SMN1; SMN2GRM1 | |
| SCHEMBL25823001 | 0.73 | CYP2A6 (0.44) | CYP2A6CYP2E1CYP3A4SMN1; SMN2GRM1 | |
| Hydrochloric Acid SCHEMBL6342651 | 0.72 | CYP1A2 (0.65) | CYP2A6CYP2E1CYP3A4SMN1; SMN2GRM1 | |
| SCHEMBL16019532 | 0.71 | GRM1 (0.42) | CYP2A6CYP2E1CYP3A4PIK3CDSMN1; SMN2 | |
| SCHEMBL9026635 | 0.70 | CYP2A6 (0.44) | CYP2A6CYP2E1CYP3A4SMN1; SMN2GRM1 | |
| SCHEMBL9025915 | 0.70 | CYP2A6 (0.44) | CYP2A6CYP2E1CYP3A4GRM1ALOX12 | |
| SCHEMBL13740923 | 0.70 | CYP2A6 (0.44) | CYP2A6CYP2E1CYP3A4SMN1; SMN2GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170267657-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2017-09-21 | — | — | US | disclosed |
| US-9708288-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2017-07-18 | — | — | US | disclosed |
| US-9591857-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2017-03-14 | — | — | US | disclosed |
| US-20160318924-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2016-11-03 | — | — | US | disclosed |
| US-20160159766-A9 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2016-06-09 | — | — | US | disclosed |
| US-20160060245-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2016-03-03 | — | — | US | disclosed |
| US-20150335022-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2015-11-26 | — | — | US | disclosed |
| US-20140162874-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2014-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160318924-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | ACHE, DDT, PTMS | CYP2A6 368/4885CYP2E1 56/4885CYP3A4 129/4885 |
| US-20160159766-A9 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | ACHE, DDT, PTMS | CYP2A6 368/4885CYP2E1 56/4885CYP3A4 129/4885 |
| US-20150335022-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | ACHE, DDT, PTMS | CYP2A6 368/4885CYP2E1 56/4885CYP3A4 129/4885 |
| US-20170267657-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | ACHE, DDT, PTMS | CYP2A6 368/4885CYP2E1 56/4885CYP3A4 129/4885 |
| US-20140162874-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | ACHE, DDT, PTMS | CYP2A6 368/4885CYP2E1 56/4885CYP3A4 129/4885 |
| US-20160060245-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | ACHE, DDT, PTMS | CYP2A6 368/4885CYP2E1 56/4885CYP3A4 129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.