Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20066062 | 1.00 | MAPK1 (0.43) | MAPK1CHRM2CHRM4KCNH2GAA | |
| SCHEMBL30179395 | 0.88 | OPRM1 (0.46) | MAPK1CHRM2CHRM4KCNH2GAA | |
| SCHEMBL20066046 | 0.88 | OPRM1 (0.46) | MAPK1CHRM2CHRM4KCNH2GAA | |
| SCHEMBL20066048 | 0.87 | SMN1; SMN2 (0.49) | MAPK1CHRM2CHRM4GAAALOX12 | |
| SCHEMBL30179202 | 0.87 | SMN1; SMN2 (0.49) | MAPK1CHRM2CHRM4GAAALOX12 | |
| SCHEMBL23778385 | 0.86 | KDM4E (0.41) | HRH3KDM4EALDH1A1 | |
| SCHEMBL20066051 | 0.84 | ALDH1A1 (0.45) | MAPK1GAAALOX12SMN1; SMN2HRH3 | |
| SCHEMBL30179404 | 0.84 | ALDH1A1 (0.45) | MAPK1GAAALOX12SMN1; SMN2HRH3 | |
| SCHEMBL20066049 | 0.84 | SMN1; SMN2 (0.48) | MAPK1CHRM2CHRM4GAAALOX12 | |
| SCHEMBL30179192 | 0.84 | SMN1; SMN2 (0.48) | MAPK1CHRM2CHRM4GAAALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109996792-B | Heterocyclic compounds having activity as modulators of muscarinic M1 and/or M4 receptors in the treatment of CNS diseases and pain | 赫普泰雅治疗有限公司 | 2023-02-17 | — | — | CN | disclosed |