4-Methoxysalicylic Acid

4-Methoxysalicylic Acid

SCHEMBL30179513

COc1ccc(C(=O)O)c(O)c1.[K-4]

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.72
RAB9A P51151 2/20 0.72
ALDH1A1 P00352 5/20 0.70
CYP3A4 P08684 4/20 0.70
HPGD P15428 3/20 0.70
MAPK1 P28482 3/20 0.70
LMNA P02545 4/20 0.65
CYP2C19 P33261 3/20 0.65
CYP1A2 P05177 2/20 0.65
PGR P06401 2/20 0.65
SLC6A2 P23975 2/20 0.65
CYP2D6 P10635 1/20 0.65
PDE4A P27815 1/20 0.65
HRH1 P35367 1/20 0.65
HTT P42858 1/20 0.65
SLC6A3 Q01959 1/20 0.65
PDE4D Q08499 1/20 0.65
ADORA3 P0DMS8 1/20 0.62
AR P10275 1/20 0.62
CHRM1 P11229 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Methoxysalicylic Acid SCHEMBL483346 0.98 NPC1 (0.75) NPC1RAB9AALDH1A1CYP3A4HPGD
4-Methoxysalicylic Acid SCHEMBL15271279 0.96 NPC1 (0.72) NPC1RAB9AALDH1A1CYP3A4HPGD
4-Methoxysalicylic Acid SCHEMBL3212855 0.96 NPC1 (0.72) NPC1RAB9AALDH1A1CYP3A4HPGD
4-Methoxysalicylic Acid SCHEMBL3212873 0.96 NPC1 (0.72) NPC1RAB9AALDH1A1CYP3A4HPGD
4-Methoxysalicylic Acid SCHEMBL15271283 0.96 NPC1 (0.72) NPC1RAB9AALDH1A1CYP3A4HPGD
4-Methoxysalicylic Acid SCHEMBL30490367 0.96 NPC1 (0.72) NPC1RAB9AALDH1A1CYP3A4HPGD
SCHEMBL10596186 0.87 NPC1 (0.61) NPC1RAB9AALDH1A1CYP3A4HPGD
SCHEMBL1447373 0.85 NPC1 (0.72) NPC1RAB9AALDH1A1CYP3A4HPGD
SCHEMBL29365072 0.84 NPC1 (1.00) NPC1RAB9AALDH1A1CYP3A4HPGD
SCHEMBL38652 0.84 NPC1 (1.00) NPC1RAB9AALDH1A1CYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022228475-A1 ASCORBIC ACID POLYPEPTIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF 禾美生物科技(浙江)有限公司 2022-11-03 WO disclosed