4-Methoxysalicylic Acid

4-Methoxysalicylic Acid

SCHEMBL30490367

COc1ccc(C(=O)O)c(O)c1.[K]

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.72
RAB9A P51151 4/20 0.72
HPGD P15428 3/20 0.70
ALDH1A1 P00352 3/20 0.70
MAPK1 P28482 3/20 0.70
CYP3A4 P08684 3/20 0.70
LMNA P02545 4/20 0.65
CYP2C19 P33261 3/20 0.65
CYP1A2 P05177 2/20 0.65
PGR P06401 2/20 0.65
SLC6A2 P23975 2/20 0.65
CYP2D6 P10635 1/20 0.65
PDE4A P27815 1/20 0.65
HRH1 P35367 1/20 0.65
HTT P42858 1/20 0.65
SLC6A3 Q01959 1/20 0.65
PDE4D Q08499 1/20 0.65
ADORA3 P0DMS8 1/20 0.62
AR P10275 1/20 0.62
CHRM1 P11229 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Methoxysalicylic Acid SCHEMBL3212873 1.00 NPC1 (0.72) NPC1RAB9AHPGDALDH1A1MAPK1
4-Methoxysalicylic Acid SCHEMBL483346 0.98 NPC1 (0.75) NPC1RAB9AHPGDALDH1A1MAPK1
4-Methoxysalicylic Acid SCHEMBL15271279 0.96 NPC1 (0.72) NPC1RAB9AHPGDALDH1A1MAPK1
4-Methoxysalicylic Acid SCHEMBL3212855 0.96 NPC1 (0.72) NPC1RAB9AHPGDALDH1A1MAPK1
4-Methoxysalicylic Acid SCHEMBL15271283 0.96 NPC1 (0.72) NPC1RAB9AHPGDALDH1A1MAPK1
4-Methoxysalicylic Acid SCHEMBL30179513 0.96 NPC1 (0.72) NPC1RAB9AHPGDALDH1A1MAPK1
SCHEMBL10596186 0.87 NPC1 (0.61) NPC1RAB9AHPGDALDH1A1MAPK1
SCHEMBL29365072 0.84 NPC1 (1.00) NPC1RAB9AHPGDALDH1A1MAPK1
SCHEMBL38652 0.84 NPC1 (1.00) NPC1RAB9AHPGDALDH1A1MAPK1
SCHEMBL1514997 0.84 NPC1 (1.00) NPC1RAB9AHPGDALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240016726-A1 OIL-IN-WATER EMULSION COSMETIC SHISEIDO COMPANY, LTD. (JP) 2024-01-18 US disclosed
CN-116284507-A Gamma-cyclodextrin two-dimensional porous organic polymer and preparation method and application thereof 安徽大学 2023-06-23 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240016726-A1 OIL-IN-WATER EMULSION COSMETIC TYR, MITF, VAPA NPC1 2688/4885RAB9A 2262/4885HPGD 4101/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.