SCHEMBL10596186

SCHEMBL10596186

COc1ccc(Oc2ccc(C(=O)O)c(O)c2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.61
RAB9A P51151 2/20 0.61
CYP3A4 P08684 5/20 0.59
ALDH1A1 P00352 4/20 0.59
HPGD P15428 4/20 0.59
MAPK1 P28482 3/20 0.59
LMNA P02545 3/20 0.55
CYP2C19 P33261 3/20 0.55
CYP1A2 P05177 2/20 0.55
PGR P06401 2/20 0.55
SLC6A2 P23975 2/20 0.55
CYP2D6 P10635 1/20 0.55
PDE4A P27815 1/20 0.55
HRH1 P35367 1/20 0.55
HTT P42858 1/20 0.55
SLC6A3 Q01959 1/20 0.55
PDE4D Q08499 1/20 0.55
LTA4H P09960 1/20 0.55
TSHR P16473 2/20 0.53
CA12 O43570 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Methoxysalicylic Acid SCHEMBL483346 0.89 NPC1 (0.75) NPC1RAB9ACYP3A4ALDH1A1HPGD
SCHEMBL14213143 0.89 ALDH1A1 (0.65) NPC1RAB9ACYP3A4ALDH1A1HPGD
4-Methoxysalicylic Acid SCHEMBL30179513 0.87 NPC1 (0.72) NPC1RAB9ACYP3A4ALDH1A1HPGD
4-Methoxysalicylic Acid SCHEMBL15271279 0.87 NPC1 (0.72) NPC1RAB9ACYP3A4ALDH1A1HPGD
4-Methoxysalicylic Acid SCHEMBL3212873 0.87 NPC1 (0.72) NPC1RAB9ACYP3A4ALDH1A1HPGD
4-Methoxysalicylic Acid SCHEMBL30490367 0.87 NPC1 (0.72) NPC1RAB9ACYP3A4ALDH1A1HPGD
4-Methoxysalicylic Acid SCHEMBL15271283 0.87 NPC1 (0.72) NPC1RAB9ACYP3A4ALDH1A1HPGD
4-Methoxysalicylic Acid SCHEMBL3212855 0.87 NPC1 (0.72) NPC1RAB9ACYP3A4ALDH1A1HPGD
SCHEMBL9770388 0.86 XDH (0.64) NPC1RAB9AALDH1A1CYP2C19CYP1A2
SCHEMBL523820 0.86 POLB (0.63) NPC1RAB9AALDH1A1LMNALTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4855278-A Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1989-08-08 US disclosed