SCHEMBL301798

SCHEMBL301798

CCCNS(=O)(=O)c1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.68
SMN1; SMN2 Q16637 2/20 0.68
LMNA P02545 2/20 0.68
KDM4E B2RXH2 1/20 0.68
PKM P14618 1/20 0.68
CA12 O43570 2/20 0.67
CA9 Q16790 2/20 0.67
CA1 P00915 2/20 0.67
CA2 P00918 2/20 0.67
TSHR P16473 1/20 0.65
MAPK1 P28482 1/20 0.61
NPSR1 Q6W5P4 1/20 0.59
KEAP1 Q14145 1/20 0.57
TDP1 Q9NUW8 1/20 0.54
TBXA2R P21731 1/20 0.54
GAA P10253 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL12481388 0.98 ALDH1A1 (0.66) ALDH1A1SMN1; SMN2LMNAKDM4EPKM
Hydrochloric Acid SCHEMBL7362553 0.98 ALDH1A1 (0.66) ALDH1A1SMN1; SMN2LMNAKDM4EPKM
SCHEMBL7926317 0.93 ALDH1A1 (0.59) ALDH1A1SMN1; SMN2LMNAKDM4EPKM
SCHEMBL28717153 0.89 CA12 (0.64) ALDH1A1SMN1; SMN2LMNAKDM4EPKM
SCHEMBL8851674 0.89 ALDH1A1 (0.59) ALDH1A1SMN1; SMN2LMNAKDM4EPKM
SCHEMBL27712513 0.88 ALDH1A1 (0.76) ALDH1A1SMN1; SMN2LMNAKDM4EPKM
SCHEMBL51729 0.88 ALDH1A1 (0.76) ALDH1A1SMN1; SMN2LMNAKDM4EPKM
SCHEMBL8349568 0.87 ALDH1A1 (0.79) ALDH1A1SMN1; SMN2LMNAKDM4EPKM
Methane SCHEMBL27933203 0.86 ALDH1A1 (0.73) ALDH1A1SMN1; SMN2LMNAKDM4EPKM
Benzene SCHEMBL27648656 0.86 ALDH1A1 (0.73) ALDH1A1SMN1; SMN2LMNAKDM4EPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 477 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260022096-A1 NOVEL SULFONAMIDES AND THEIR USE AS NEUROPROTECTIVE AND/OR NEURORESTORATIVE AGENTS GENECODE (EE) 2026-01-22 US claimed
US-12515397-B2 Three-dimensional printed part PERIDOT PRINT LLC (US) 2026-01-06 US claimed
US-20240042680-A1 THREE-DIMENSIONAL PRINTED PART PERIDOT PRINT LLC 2024-02-08 US claimed
US-11801631-B2 Three-dimensional printed part HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2023-10-31 US claimed
US-20220009161-A1 THREE-DIMENSIONAL PRINTING HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2022-01-13 US claimed
CN-113527152-A Biphenylsulfonamide compound and method for preventing and treating crop pests by using same 西北农林科技大学 2021-10-22 CN claimed
CN-113227036-A Ethylenediamine compound and application thereof 中国人民解放军军事科学院军事医学研究院 2021-08-06 CN claimed
US-20210197445-A1 THREE-DIMENSIONAL PRINTED PART HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2021-07-01 US claimed
CN-108164503-B A kind of heteroaromatic and the disubstituted benzenesulfonamides of alkyl side chain and its preparing the application in anti-influenza A virus medicament 武汉大学 2019-09-17 CN claimed
CN-108440856-A Dye-colored body and method for producing same 谦华科技股份有限公司 2018-08-24 CN claimed
WO-2005030209-A1 PYRIDINE DERIVATIVES AND USE THEREOF AS UROTENSIN II ANTAGONISTS ACTELION PHARMACEUTICALS LTD (CH) 2005-04-07 WO claimed
WO-2005026129-A1 PHARMACEUTICALLY ACTIVE 4,6-DISUBSTITUTED AMINOPYRIMIDINE DERIVATIVES AS MODULATORS OF PROTEIN KINASES GPC BIOTECH AG (DE) 2005-03-24 WO claimed
WO-2005014596-A1 7-SUBSTITUTED 3-NITRO-PYRAZOLO `1,5-A! PYRIMIDINES FERRER INTERNACIONAL, S.A. (ES) 2005-02-17 WO claimed
US-6828375-B2 Containing a thermoplastic elastomer grafted with maleic anhydride, carbon black powder, sulfonamide based material, and alkanedioic acid HYUNDAI MOTOR COMPANY (KR) 2004-12-07 US claimed
EP-1165866-B1 ABRASIVE FILAMENTS OF PLASTICIZED POLYAMIDES DU PONT (US) 2004-01-28 EP claimed
EP-1283832-A1 INHIBITORS OF 11-BETA-HYDROXY STEROID DEHYDROGENASE TYPE 1 BIOVITRUM AB (SE) 2003-02-19 EP claimed
US-20020128373-A1 Electroconductive polyamide resin composition and molded product for motor component prepared therefrom HYUNDAI MOTOR COMPANY (KR) 2002-09-12 US claimed
WO-2001090092-A1 INHIBITORS OF 11-BETA-HYDROXY STEROID DEHYDROGENASE TYPE 1 BIOVITRUM AB (SE) 2001-11-29 WO claimed
US-5437690-A Using an n-alkyl aromatic sulfonamide as dye promoter in dyeing aromatic polyamides, polybenzimidazoles, polyimides SPRINGS INDUSTRIES, INC. (US) 1995-08-01 US claimed
US-4968737-A Molding compounds comprising a thermoplastically processible aromatic polyamide HUELS AKTIENGESELLSCHAFT (DE) 1990-11-06 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260022096-A1 NOVEL SULFONAMIDES AND THEIR USE AS NEUROPROTECTIVE AND/OR NEURORESTORATIVE AGENTS CNR1, CDR2, SMN1; SMN2 ALDH1A1 1383/4885SMN1; SMN2 3/4885LMNA 1359/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.