Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.79 |
| ▸ | PKM | P14618 | 3/20 | 0.79 |
| ▸ | LMNA | P02545 | 2/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.79 |
| ▸ | TSHR | P16473 | 1/20 | 0.73 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.63 |
| ▸ | CA12 | O43570 | 2/20 | 0.60 |
| ▸ | CA9 | Q16790 | 2/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL578633 | 0.98 | ALDH1A1 (0.82) | ALDH1A1PKMLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL578728 | 0.98 | ALDH1A1 (0.82) | ALDH1A1PKMLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL579136 | 0.98 | ALDH1A1 (0.82) | ALDH1A1PKMLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL633906 | 0.98 | ALDH1A1 (0.82) | ALDH1A1PKMLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL5020960 | 0.98 | ALDH1A1 (0.82) | ALDH1A1PKMLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL578832 | 0.98 | ALDH1A1 (0.82) | ALDH1A1PKMLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL1279062 | 0.98 | ALDH1A1 (0.82) | ALDH1A1PKMLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL51729 | 0.94 | ALDH1A1 (0.76) | ALDH1A1PKMLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL27712513 | 0.94 | ALDH1A1 (0.76) | ALDH1A1PKMLMNAKDM4ESMN1; SMN2 | |
| Bicarbonate SCHEMBL9492528 | 0.93 | ALDH1A1 (0.74) | ALDH1A1PKMLMNAKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 204 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107778239-A | A kind of synthetic method of phenanthridines and its derivative | 浙江工业大学 | 2018-03-09 | — | — | CN | claimed |
| US-9790321-B2 | Heat resistant polyethylene terephthalate and a process for the preparation of the same | ESTER INDUSTRIES LIMITED (IN) | 2017-10-17 | — | — | US | claimed |
| US-20160168321-A1 | HEAT RESISTANT POLYETHYLENE TEREPHTHALATE AND A PROCESS FOR THE PREPARATION OF THE SAME | ESTER INDUSTRIES LIMITED (IN) | 2016-06-16 | — | — | US | claimed |
| EP-2999733-A1 | HEAT RESISTANT POLYETHYLENE TEREPHTHALATE AND A PROCESS FOR THE PREPARATION OF THE SAME | Ester Industries Limited (IN) | 2016-03-30 | — | — | EP | claimed |
| CN-101111240-B | Isolation of n-butylbenzenesulfonamide, synthesis of benzenesulfonamide derivatives, and use of n-butylbenzenesulfonamide and benzenesulfonamide derivatives for the treatment of benign prostate hyperp | LOHMANN THERAPIE SYST LTS | 2011-09-21 | — | — | CN | claimed |
| US-7956216-B2 | Benzoyl urea derivatives mimicing BH3-only proteins, able to interact with a Bcl-2 protein | THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (AU) | 2011-06-07 | — | — | US | claimed |
| US-7700654-B2 | Isolation of N-butylbenzenesulfonamide, synthesis of benzenesulfonamide derivatives, and use of N-butylbenzenesulfonamide and benzenesulfonamide derivatives for treating benign prostatic hyperplasia and/or prostate carcinoma | LTS LOHMANN THERAPIE-SYSTEME AG (DE) | 2010-04-20 | — | — | US | claimed |
| US-20080153802-A1 | Alpha-helical mimetics | THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (AU) | 2008-06-26 | — | — | US | claimed |
| EP-1888517-A1 | NOVEL 8-SULFONYLAMINO-3 AMINOSUBSTITUTED CHROMAN OR TETRAHYDRONAPHTALENE DERIVATIVES MODULATING THE 5HT6 RECEPTOR | AstraZeneca AB (SE) | 2008-02-20 | — | — | EP | claimed |
| EP-1763509-A1 | ALPHA-HELICAL MIMETICS | THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (AU) | 2007-03-21 | — | — | EP | claimed |
| WO-2006126939-A1 | NOVEL 8-SULFONYLAMINO-3 AMINOSUBSTITUTED CHROMAN OR TETRAHYDRONAPHTALENE DERIVATIVES MODULATING THE 5HT6 RECEPTOR | ASTRAZENECA AB (SE) | 2006-11-30 | — | — | WO | claimed |
| WO-2006002474-A1 | ALPHA-HELICAL MIMETICS | THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (AU) | 2006-01-12 | — | — | WO | claimed |
| CN-118439980-B | Synthesis method of alpha-cyano sulfonamide derivative | 浙江工业大学 | 2025-04-08 | — | — | CN | disclosed |
| CN-118439980-A | Synthesis method of alpha-cyano sulfonamide derivative | 浙江工业大学 | 2024-08-06 | — | — | CN | disclosed |
| US-11815815-B2 | Composition for forming silicon-containing resist underlayer film removable by wet process | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2023-11-14 | — | — | US | disclosed |
| US-20220187709-A1 | FILM-FORMING COMPOSITION | NISSAN CHEMICAL CORPORATION (JP) | 2022-06-16 | — | — | US | disclosed |
| EP-0068968-A1 | Medicines containing as active ingredients compounds of the arylbenzenesulfonamide-type, and processes for their preparation | CHOAY S.A. (FR) | 1983-01-05 | — | — | EP | disclosed |
| US-4123411-A | Plasticized composition of copolyetherester elastomer and aromatic sulfonamide | MONSANTO COMPANY (US) | 1978-10-31 | — | — | US | disclosed |
| US-4053458-A | INHIBITORS | UOP INC. (US) | 1977-10-11 | — | — | US | disclosed |
| US-4022828-A | BIS-(SULFONAMIDO)-SULFIDES | UNIVERSAL OIL PRODUCTS COMPANY (US) | 1977-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080153802-A1 | Alpha-helical mimetics | BID, BAX, BAD | ALDH1A1 4208/4885PKM 3582/4885LMNA 454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.