Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 5/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | CCR4 | P51679 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24846895 | 0.82 | GPR119 (0.42) | BRD4ALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL24847992 | 0.78 | HTR7 (0.33) | HTR7DRD2HTR1AADRA2AADRA2B | |
| SCHEMBL29751443 | 0.75 | AAK1 (0.39) | BRD4BRPF1 | |
| SCHEMBL24607488 | 0.75 | AAK1 (0.39) | BRD4BRPF1 | |
| SCHEMBL29991526 | 0.71 | CYP2D6 (0.33) | HTR7DRD2HTR1AADRA2AADRA2B | |
| SCHEMBL23832583 | 0.70 | CSNK2A2 (0.42) | BRD4ALDH1A1LMNAKMT2A | |
| SCHEMBL14992295 | 0.70 | DAO (0.41) | HTR7HTR1ABRD4ALDH1A1LMNA | |
| SCHEMBL25337018 | 0.67 | GPR119 (0.41) | ALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL13015476 | 0.67 | CYP19A1 (0.47) | HTR7CCR4BRD4ALDH1A1MAPT | |
| SCHEMBL23832667 | 0.65 | MEN1 (0.48) | ALDH1A1MAPTLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023278759-A1 | MK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |