Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.38 |
| ▸ | CXCR3 | P49682 | 5/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28954745 | 1.00 | HDAC1 (0.40) | HDAC1HDAC6HDAC4TP53HTR1A | |
| SCHEMBL22391888 | 0.86 | GRM2 (0.42) | HDAC1HDAC6HDAC4TP53HTR1A | |
| SCHEMBL30455263 | 0.86 | GRM2 (0.42) | HDAC1HDAC6HDAC4TP53HTR1A | |
| SCHEMBL1513289 | 0.86 | DBH (0.47) | ALDH1A1KMT2ATSHRMEN1PKM | |
| SCHEMBL22392024 | 0.79 | HTR3E (0.51) | HTR1AHTR2AHTR7HTR6MAOB | |
| SCHEMBL16591995 | 0.75 | MAPT (0.45) | ALDH1A1KMT2AMAPTPKMDBH | |
| SCHEMBL24334961 | 0.71 | KMT2A (0.48) | HTR6ALDH1A1KMT2A | |
| SCHEMBL22824293 | 0.71 | HTR2C (0.34) | HTR2ACXCR3KMT2A | |
| SCHEMBL29365816 | 0.71 | HTR2C (0.34) | HTR2ACXCR3KMT2A | |
| SCHEMBL30424558 | 0.71 | KMT2A (0.48) | HTR6ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115703766-A | GLP-1 receptor agonists and uses thereof | 天地恒一制药股份有限公司 | 2023-02-17 | — | — | CN | disclosed |