Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | STAT6 | P42226 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 7/20 | 0.41 |
| ▸ | FLT3 | P36888 | 5/20 | 0.41 |
| ▸ | FYN | P06241 | 5/20 | 0.41 |
| ▸ | DBH | P09172 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30424558 | 0.83 | KMT2A (0.48) | KMT2ASTAT6SRCFYNHRH3 | |
| SCHEMBL24334961 | 0.83 | KMT2A (0.48) | KMT2ASTAT6SRCFYNHRH3 | |
| SCHEMBL15687459 | 0.80 | STAT6 (0.40) | MAPTTHRBSTAT6SRCFLT3 | |
| SCHEMBL16794770 | 0.79 | ENPP2 (0.47) | MAPTTHRBKMT2AENPP2ALDH1A1 | |
| SCHEMBL24334965 | 0.78 | CYP11B1 (0.39) | MAPTKMT2AALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL29365816 | 0.77 | HTR2C (0.34) | KMT2A | |
| SCHEMBL22824293 | 0.77 | HTR2C (0.34) | KMT2A | |
| SCHEMBL9278020 | 0.76 | TP53 (0.45) | MAPTKMT2ASTAT6SRCFLT3 | |
| SCHEMBL28954745 | 0.75 | HDAC1 (0.40) | MAPTKMT2ADBHALDH1A1PKM | |
| SCHEMBL30180530 | 0.75 | HDAC1 (0.40) | MAPTKMT2ADBHALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951026-B2 | Heterocyclic vinyl autotaxin inhibitor compounds | PHARMAKEA, INC. (US) | 2018-04-24 | — | — | US | disclosed |
| US-9951026-B2 | Heterocyclic vinyl autotaxin inhibitor compounds | PHARMAKEA, INC. (US) | 2018-04-24 | — | — | US | disclosed |
| US-9951026-B2 | Heterocyclic vinyl autotaxin inhibitor compounds | PHARMAKEA, INC. (US) | 2018-04-24 | — | — | US | disclosed |
| US-20160229809-A1 | HETEROCYCLIC VINYL AUTOTAXIN INHIBITOR COMPOUNDS | DF 2024 IP ACQUISITION, LLC | 2016-08-11 | — | — | US | disclosed |
| US-20160229809-A1 | HETEROCYCLIC VINYL AUTOTAXIN INHIBITOR COMPOUNDS | DF 2024 IP ACQUISITION, LLC | 2016-08-11 | — | — | US | disclosed |
| US-20160229809-A1 | HETEROCYCLIC VINYL AUTOTAXIN INHIBITOR COMPOUNDS | DF 2024 IP ACQUISITION, LLC | 2016-08-11 | — | — | US | disclosed |
| WO-2015042052-A1 | HETEROCYCLIC VINYL AUTOTAXIN INHIBITOR COMPOUNDS | PHARMAKEA, INC. (US) | 2015-03-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160229809-A1 | HETEROCYCLIC VINYL AUTOTAXIN INHIBITOR COMPOUNDS | ENPP2, SERPINB1, UACA | MAPT 693/4885THRB 3673/4885KMT2A 1453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.