Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 18/20 | 0.39 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24891765 | 1.00 | NAMPT (0.39) | NAMPTWNT3ANPC1ALDH1A1ALOX15 | |
| SCHEMBL24891740 | 0.91 | NPC1 (0.41) | NAMPTNPC1ALDH1A1ALOX15TSHR | |
| Hydrochloric Acid SCHEMBL30182348 | 0.90 | NPC1 (0.41) | NAMPTNPC1ALDH1A1ALOX15TSHR | |
| SCHEMBL24891713 | 0.87 | NPC1 (0.40) | NAMPTNPC1ALDH1A1ALOX15TSHR | |
| SCHEMBL30180901 | 0.87 | WNT3A (0.38) | NAMPTWNT3A | |
| SCHEMBL24891824 | 0.87 | WNT3A (0.38) | NAMPTWNT3A | |
| SCHEMBL30181109 | 0.87 | NAMPT (0.39) | NAMPTWNT3ANPC1ALDH1A1ALOX15 | |
| SCHEMBL24892130 | 0.87 | NAMPT (0.39) | NAMPTWNT3ANPC1ALDH1A1ALOX15 | |
| SCHEMBL24891674 | 0.85 | WNT3A (0.34) | NAMPTWNT3ANPC1ALDH1A1ALOX15 | |
| SCHEMBL30180922 | 0.85 | WNT3A (0.34) | NAMPTWNT3ANPC1ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | claimed |
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |