Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 11/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24891674 | 1.00 | WNT3A (0.34) | WNT3AMAPTTP53NPC1ALDH1A1 | |
| SCHEMBL30180862 | 0.95 | WNT3A (0.33) | WNT3AMAPTTP53NPC1ALDH1A1 | |
| SCHEMBL30180901 | 0.88 | WNT3A (0.38) | WNT3AMAPTTP53NAMPT | |
| SCHEMBL30180918 | 0.88 | TMPRSS2 (0.40) | NPC1RAB9ASMN1; SMN2NAMPTKDM4E | |
| SCHEMBL24891824 | 0.88 | WNT3A (0.38) | WNT3AMAPTTP53NAMPT | |
| SCHEMBL24891721 | 0.87 | NAMPT (0.31) | WNT3AMAPTTP53NAMPT | |
| SCHEMBL24891740 | 0.86 | NPC1 (0.41) | MAPTNPC1ALDH1A1ALOX15TSHR | |
| Hydrochloric Acid SCHEMBL30182348 | 0.85 | NPC1 (0.41) | MAPTTP53NPC1ALDH1A1ALOX15 | |
| SCHEMBL24891765 | 0.85 | NAMPT (0.39) | WNT3ANPC1ALDH1A1ALOX15TSHR | |
| SCHEMBL30180876 | 0.85 | NAMPT (0.39) | WNT3ANPC1ALDH1A1ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | claimed |
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |