Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
| ▸ | CASP2 | P42575 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25516067 | 0.95 | FAAH (0.57) | EPHX2FAAHDNM1LPAR1LPAR2 | |
| SCHEMBL23365838 | 0.95 | FAAH (0.57) | EPHX2FAAHDNM1LPAR1LPAR2 | |
| SCHEMBL29310916 | 0.95 | FAAH (0.57) | EPHX2FAAHDNM1LPAR1LPAR2 | |
| SCHEMBL14466906 | 0.95 | FAAH (0.57) | EPHX2FAAHDNM1LPAR1LPAR2 | |
| SCHEMBL15507477 | 0.93 | EPHX2 (0.50) | EPHX2SMN1; SMN2FAAHGAA | |
| SCHEMBL12673829 | 0.93 | EPHX2 (0.50) | EPHX2SMN1; SMN2FAAHGAA | |
| SCHEMBL15357541 | 0.93 | EPHX2 (0.50) | EPHX2SMN1; SMN2FAAHGAA | |
| SCHEMBL13147054 | 0.93 | EPHX2 (0.50) | EPHX2SMN1; SMN2FAAHGAA | |
| SCHEMBL14118063 | 0.93 | EPHX2 (0.50) | EPHX2SMN1; SMN2FAAHGAA | |
| SCHEMBL24514705 | 0.92 | EPHX2 (0.51) | EPHX2SMN1; SMN2FAAHDNM1LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4370157-A1 | ASGPR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES | Lycia Therapeutics, Inc. (US) | 2024-05-22 | — | — | EP | disclosed |
| WO-2023288033-A1 | ASGPR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES | LYCIA THERAPEUTICS, INC. (US) | 2023-01-19 | — | — | WO | disclosed |