Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.57 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.54 |
| ▸ | CASP2 | P42575 | 1/20 | 0.53 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.52 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.52 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.52 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | GLP1R | P43220 | 3/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | SELP | P16109 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25516067 | 1.00 | FAAH (0.57) | FAAHDNM1CASP2LPAR1LPAR2 | |
| SCHEMBL23365838 | 1.00 | FAAH (0.57) | FAAHDNM1CASP2LPAR1LPAR2 | |
| SCHEMBL14466906 | 1.00 | FAAH (0.57) | FAAHDNM1CASP2LPAR1LPAR2 | |
| SCHEMBL14438832 | 0.97 | FAAH (0.61) | FAAHDNM1CASP2LPAR1LPAR2 | |
| SCHEMBL14438830 | 0.97 | FAAH (0.61) | FAAHDNM1CASP2LPAR1LPAR2 | |
| SCHEMBL14438828 | 0.97 | FAAH (0.61) | FAAHDNM1CASP2LPAR1LPAR2 | |
| SCHEMBL7650140 | 0.95 | FAAH (0.62) | FAAHDNM1CASP2LPAR1LPAR2 | |
| SCHEMBL30180923 | 0.95 | EPHX2 (0.50) | FAAHDNM1CASP2LPAR1LPAR2 | |
| SCHEMBL13811075 | 0.95 | FAAH (0.62) | FAAHDNM1CASP2LPAR1LPAR2 | |
| SCHEMBL7647954 | 0.95 | FAAH (0.62) | FAAHDNM1CASP2LPAR1LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240226225-A1 | CONJUGATED HEPCIDIN MIMETICS | PROTAGONIST THERAPEUTICS, INC. (US) | 2024-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240226225-A1 | CONJUGATED HEPCIDIN MIMETICS | HAMP, SLC40A1, FTH1 | FAAH 3794/4885DNM1 963/4885CASP2 2332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.