Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 6/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 6/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30180922 | 0.88 | WNT3A (0.34) | NAMPTNPC1RAB9AKDM4EMEN1 | |
| SCHEMBL24891674 | 0.88 | WNT3A (0.34) | NAMPTNPC1RAB9AKDM4EMEN1 | |
| SCHEMBL30180862 | 0.88 | WNT3A (0.33) | TMPRSS2NAMPTNPC1RAB9AKDM4E | |
| SCHEMBL30180909 | 0.87 | TMPRSS2 (0.39) | TMPRSS2F2NAMPTJAK2JAK1 | |
| SCHEMBL24891885 | 0.86 | TMPRSS2 (0.45) | TMPRSS2F2NAMPTNPC1RAB9A | |
| SCHEMBL24669387 | 0.86 | TMPRSS2 (0.45) | TMPRSS2F2NAMPTNPC1RAB9A | |
| SCHEMBL24891672 | 0.85 | NAMPT (0.43) | TMPRSS2NAMPTBTK | |
| SCHEMBL30181035 | 0.85 | NAMPT (0.43) | TMPRSS2NAMPTBTK | |
| SCHEMBL24891727 | 0.84 | WNT3A (0.34) | TMPRSS2NAMPT | |
| SCHEMBL24891721 | 0.82 | NAMPT (0.31) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | claimed |
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |