Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | OGA | O60502 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | DNM1L | O00429 | 2/20 | 0.30 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3016578 | 0.93 | OGA (0.33) | AOC3HTR6OGANPC1RAB9A | |
| SCHEMBL3003296 | 0.92 | DNM1L (0.34) | HTR6NPC1RAB9ASMN1; SMN2DNM1L | |
| SCHEMBL3012451 | 0.90 | MAPT (0.34) | AOC3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3013236 | 0.90 | NPC1 (0.36) | NPC1RAB9ASMN1; SMN2DNM1L | |
| SCHEMBL3011686 | 0.90 | MAPT (0.35) | HTR6NPC1RAB9ASMN1; SMN2F2RL3 | |
| SCHEMBL3014046 | 0.89 | F2RL3 (0.37) | HTR6NPC1RAB9ASMN1; SMN2F2RL3 | |
| SCHEMBL3008790 | 0.89 | CACNA1G (0.33) | AOC3HTR6NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3012892 | 0.88 | DNM1L (0.32) | HTR6NPC1RAB9ASMN1; SMN2DNM1L | |
| SCHEMBL3007264 | 0.88 | MAPK1 (0.41) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3010354 | 0.87 | DNM1L (0.34) | HTR6DNM1LF2RL3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722681-B2 | N-sulfonyl thiazolylpiperazine derivatives and related N-sulfonyl heterocyclic derivatives for the treatment of neuro degenerative diseases | NV REMYND (BE) | 2014-05-13 | — | — | US | disclosed |
| US-20100197703-A1 | N-SULFONYL THIAZOLYLPIPERAZINE DERIVATIVES AND RELATED N-SULFONYL HETEROCYCLIC DERIVATIVES FOR THE TREATMENT OF NEURO DEGENERATIVE DISEASES | NV REMYND (BE) | 2010-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197703-A1 | N-SULFONYL THIAZOLYLPIPERAZINE DERIVATIVES AND RELATED N-SULFONYL HETEROCYCLIC DERIVATIVES FOR THE TREATMENT OF NEURO DEGENERATIVE DISEASES | SMN1; SMN2, HTT, SNCA | AOC3 2304/4885HTR6 1988/4885OGA 2888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.