SCHEMBL30182879

SCHEMBL30182879

CC(c1ccccc1)c1ccc(C(=O)NCC(=O)N2CCCC2)cc1

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ RAB9A P51151 3/20 0.54
▸ KMT2A Q03164 2/20 0.54
▸ SMN1; SMN2 Q16637 2/20 0.53
▸ TSHR P16473 1/20 0.50
▸ OPRK1 P41145 1/20 0.49
▸ GPR139 Q6DWJ6 1/20 0.48
▸ MEN1 O00255 1/20 0.47
▸ ATM Q13315 1/20 0.47
▸ NPC1 O15118 1/20 0.47
▸ GAA P10253 1/20 0.47
▸ ALDH1A1 P00352 1/20 0.46
▸ L3MBTL1 Q9Y468 1/20 0.46
▸ P2RY12 Q9H244 1/20 0.46
▸ OPRD1 P41143 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1442608 0.85 RAB9A (0.70) RAB9AKMT2ASMN1; SMN2TSHRNPC1
SCHEMBL3275319 0.83 RAB9A (0.68) RAB9AKMT2ASMN1; SMN2TSHRNPC1
SCHEMBL13058919 0.81 RAB9A (0.59) RAB9AKMT2ASMN1; SMN2TSHRNPC1
SCHEMBL30182732 0.81 RAB9A (0.55) RAB9AKMT2ASMN1; SMN2TSHRNPC1
SCHEMBL30182835 0.79 RAB9A (0.69) RAB9AKMT2ASMN1; SMN2TSHRNPC1
SCHEMBL31324117 0.79 DPP4 (0.60) RAB9ASMN1; SMN2NPC1GAA
SCHEMBL13058939 0.78 RAB9A (0.67) RAB9AKMT2ASMN1; SMN2TSHRNPC1
SCHEMBL3861151 0.77 KMT2A (0.61) RAB9AKMT2ASMN1; SMN2MEN1ATM
SCHEMBL20924642 0.75 KMT2A (0.65) RAB9AKMT2ASMN1; SMN2ALDH1A1L3MBTL1
SCHEMBL20924603 0.75 SMN1; SMN2 (0.60) RAB9AKMT2ASMN1; SMN2TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12479856-B2 Pharmaceutical compounds for the treatment of complement mediated disorders ACHILLION PHARMACEUTICALS, INC. (US) 2025-11-25 — — US disclosed
US-20230085372-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS ACHILLION PHARMACEUTICALS, INC. (US) 2023-03-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12479856-B2 Pharmaceutical compounds for the treatment of complement mediated disorders C5, CFH, C1QBP RAB9A 1696/4885KMT2A 4482/4885SMN1; SMN2 659/4885
US-20230085372-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS C5, CFH, C1QBP RAB9A 1696/4885KMT2A 4482/4885SMN1; SMN2 659/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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