SCHEMBL30183062

SCHEMBL30183062

CCC(=O)N1CCC(NC(N)=O)CC1

nearest known ligand 0.66

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 19/20 0.66
EPHX1 P07099 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17316270 0.84 EPHX2 (0.68) EPHX2EPHX1
SCHEMBL25933285 0.83 EPHX2 (0.46) EPHX2EPHX1
SCHEMBL26251778 0.81 EPHX2 (0.64) EPHX2EPHX1
SCHEMBL25930914 0.81 EPHX2 (0.64) EPHX2EPHX1
SCHEMBL13306160 0.79 EPHX2 (0.62) EPHX2EPHX1
SCHEMBL12507086 0.79 EPHX2 (0.62) EPHX2EPHX1
SCHEMBL27969934 0.79 EPHX2 (0.62) EPHX2EPHX1
SCHEMBL2719520 0.79 EPHX2 (1.00) EPHX2EPHX1
SCHEMBL2730613 0.79 EPHX2 (1.00) EPHX2EPHX1
SCHEMBL27726136 0.79 GAA (0.63)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118019728-A Compounds as soluble epoxide hydrolase inhibitors 巴塞罗那大学 2024-05-10 CN claimed
CN-112888674-B Polycyclic compounds as soluble epoxide hydrolase inhibitors 巴塞罗那大学 2023-06-30 CN claimed
CN-118019728-A Compounds as soluble epoxide hydrolase inhibitors 巴塞罗那大学 2024-05-10 CN disclosed
CN-112888674-B Polycyclic compounds as soluble epoxide hydrolase inhibitors 巴塞罗那大学 2023-06-30 CN disclosed
WO-2023012610-A1 FORMULATIONS, COMPOSITIONS AND METHODS FOR THE TREATMENT OF STROKE AVACA PHARMA PRIVATE LIMITED (IN) 2023-02-09 WO disclosed