Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | NOS3 | P29474 | 1/20 | 0.55 |
| ▸ | NOS2 | P35228 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | PLG | P00747 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.51 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6185775 | 0.87 | GAA (0.59) | GAAL3MBTL1THRBATMKMT2A | |
| SCHEMBL1493923 | 0.87 | GAA (0.59) | GAAL3MBTL1THRBATMKMT2A | |
| SCHEMBL6969097 | 0.85 | L3MBTL1 (0.64) | GAAL3MBTL1THRBATMKMT2A | |
| SCHEMBL16152211 | 0.83 | L3MBTL1 (0.62) | GAAL3MBTL1THRBATMKMT2A | |
| SCHEMBL6264941 | 0.83 | L3MBTL1 (0.62) | GAAL3MBTL1THRBATMKMT2A | |
| SCHEMBL1128414 | 0.83 | THRB (0.66) | GAAL3MBTL1THRBATMKMT2A | |
| SCHEMBL27458570 | 0.82 | L3MBTL1 (0.60) | GAAL3MBTL1THRBATMKMT2A | |
| SCHEMBL12184203 | 0.82 | L3MBTL1 (0.60) | GAAL3MBTL1THRBATMKMT2A | |
| SCHEMBL14349527 | 0.81 | L3MBTL1 (0.56) | GAAL3MBTL1THRBATMKMT2A | |
| Hydrochloric Acid SCHEMBL17074783 | 0.81 | THRB (0.64) | GAAL3MBTL1THRBATMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101161645-B | Urea derivatives as well as preparation method and uses thereof | NANJING UNIVERSITY OF TECHNOLOGY | 2010-06-23 | — | — | CN | claimed |
| CN-101161645-B | Urea derivatives as well as preparation method and uses thereof | NANJING UNIVERSITY OF TECHNOLOGY | 2010-06-23 | — | — | CN | disclosed |
| CN-101161645-A | Urea derivatives as well as preparation method and uses thereof | NANJING UNIVERSITY OF TECHNOLOGY (CN) | 2008-04-16 | — | — | CN | disclosed |