Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 19/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30183062 | 0.83 | EPHX2 (0.66) | EPHX2EPHX1 | |
| SCHEMBL8486131 | 0.82 | EPHX2 (0.44) | EPHX2EPHX1 | |
| SCHEMBL24322890 | 0.79 | SMN1; SMN2 (0.55) | — | |
| SCHEMBL12450224 | 0.79 | GNAI3 (0.51) | EPHX2LMNA | |
| SCHEMBL13306160 | 0.77 | EPHX2 (0.62) | EPHX2EPHX1 | |
| SCHEMBL13119145 | 0.77 | ALDH1A1 (0.41) | EPHX2EPHX1 | |
| SCHEMBL2606045 | 0.77 | ALDH1A1 (0.60) | LMNA | |
| SCHEMBL23698639 | 0.76 | NCF1 (0.44) | EPHX2LMNA | |
| SCHEMBL16322031 | 0.74 | EPHX1 (0.42) | EPHX2EPHX1 | |
| SCHEMBL24098153 | 0.74 | EPHX2 (0.40) | EPHX2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242548-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242548-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | KRAS, HRAS, NRAS | EPHX2 2775/4885EPHX1 2274/4885LMNA 2600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.