Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 2/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.32 |
| ▸ | CDK2 | P24941 | 2/20 | 0.32 |
| ▸ | CCND3 | P30281 | 2/20 | 0.32 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20649193 | 1.00 | L3MBTL1 (0.38) | L3MBTL1CDK4CCNA2CDK2CCND3 | |
| SCHEMBL30183122 | 0.89 | GRM5 (0.40) | NPC1RAB9AKDM4EGAA | |
| SCHEMBL20648932 | 0.89 | GRM5 (0.40) | NPC1RAB9AKDM4EGAA | |
| SCHEMBL20648952 | 0.88 | RAB9A (0.44) | POLBNPC1RAB9AKDM4E | |
| SCHEMBL30183509 | 0.88 | RAB9A (0.44) | POLBNPC1RAB9AKDM4E | |
| SCHEMBL20649369 | 0.87 | CSNK2A1 (0.40) | CSNK2A1GAA | |
| SCHEMBL30183295 | 0.87 | CSNK2A1 (0.40) | CSNK2A1GAA | |
| SCHEMBL20649021 | 0.87 | MAPKAPK2 (0.41) | PIM1PIM3 | |
| SCHEMBL30183144 | 0.87 | MAPKAPK2 (0.41) | PIM1PIM3 | |
| SCHEMBL20649045 | 0.87 | CSNK2A1 (0.37) | CDK2CSNK2A1NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110997678-B | Pyrazoloquinazoline derivatives as choline kinase inhibitors | 内尔维亚诺医疗科学公司 | 2023-02-21 | — | — | CN | claimed |
| CN-110997678-B | Pyrazoloquinazoline derivatives as choline kinase inhibitors | 内尔维亚诺医疗科学公司 | 2023-02-21 | — | — | CN | disclosed |