Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CBX7 | O95931 | 1/20 | 0.40 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.40 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.40 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.40 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23577908 | 1.00 | CASP3 (0.44) | CASP3CHRM5POLBSMN1; SMN2CBX7 | |
| SCHEMBL23591099 | 0.84 | CASP3 (0.46) | CASP3POLBSMN1; SMN2CBX7CDYL2 | |
| SCHEMBL30183749 | 0.83 | CASP3 (0.45) | CASP3POLBSMN1; SMN2CBX7CDYL2 | |
| SCHEMBL23577606 | 0.83 | CASP3 (0.45) | CASP3POLBSMN1; SMN2CBX7CDYL2 | |
| SCHEMBL23591296 | 0.82 | CASP3 (0.44) | CASP3POLBSMN1; SMN2CBX7CDYL2 | |
| SCHEMBL38660490 | 0.79 | CASP3 (0.41) | CASP3POLBSMN1; SMN2CBX7CDYL2 | |
| SCHEMBL23578330 | 0.77 | CASP3 (0.49) | CASP3POLBSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL30183667 | 0.77 | CASP3 (0.49) | CASP3POLBSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL16377147 | 0.76 | RAD52 (0.63) | SMN1; SMN2CBX7CDYL2CDYLCDY1; CDY1B | |
| SCHEMBL16324200 | 0.76 | CASP3 (0.50) | CASP3POLBSMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605476-A | Substituted tricyclic compounds | 鲁宾有限公司（IN） | 2023-01-13 | — | — | CN | disclosed |