Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | CBX7 | O95931 | 2/20 | 0.50 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.50 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NQO1 | P15559 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25890248 | 0.80 | RAD52 (0.68) | RAD52ALDH1A1CBX7CDY1; CDY1BMAPK1 | |
| SCHEMBL18415222 | 0.78 | RAD52 (1.00) | RAD52ALDH1A1CBX7CDY1; CDY1BMAPK1 | |
| SCHEMBL16377157 | 0.77 | ALDH1A1 (0.61) | ALDH1A1CDY1; CDY1BMAPK1CDYL2CDYL | |
| SCHEMBL4728612 | 0.76 | ALDH1A1 (0.63) | ALDH1A1MAPTTHRBSMN1; SMN2 | |
| SCHEMBL23577908 | 0.76 | CASP3 (0.44) | RAD52ALDH1A1CBX7CDY1; CDY1BCDYL2 | |
| SCHEMBL30183706 | 0.76 | CASP3 (0.44) | RAD52ALDH1A1CBX7CDY1; CDY1BCDYL2 | |
| SCHEMBL3201165 | 0.76 | ALDH1A1 (0.65) | RAD52ALDH1A1CBX7CDY1; CDY1BMAPK1 | |
| SCHEMBL16377137 | 0.74 | ALDH1A1 (0.58) | ALDH1A1MAPTTSHRLMNASMN1; SMN2 | |
| SCHEMBL16377155 | 0.74 | MAPT (0.46) | ALDH1A1MAPTMEN1KMT2ATSHR | |
| SCHEMBL38659116 | 0.73 | RAD52 (0.59) | RAD52ALDH1A1CBX7CDY1; CDY1BMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8933248-B2 | 3-substituted-3-hydroxy oxindole derivatives and process for preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-01-13 | — | — | US | disclosed |
| US-8933248-B2 | 3-substituted-3-hydroxy oxindole derivatives and process for preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-01-13 | — | — | US | disclosed |