Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.77 |
| ▸ | RAB9A | P51151 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | PARP1 | P09874 | 1/20 | 0.55 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.55 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14880002 | 1.00 | MEN1 (0.77) | MEN1KMT2ARAB9AALDH1A1NPC1 | |
| SCHEMBL11754128 | 0.87 | KMT2A (1.00) | MEN1KMT2ARAB9AALDH1A1NPC1 | |
| SCHEMBL14879671 | 0.84 | MEN1 (0.82) | MEN1KMT2ARAB9AALDH1A1NPC1 | |
| SCHEMBL863169 | 0.82 | RAB9A (0.71) | MEN1KMT2ARAB9AALDH1A1NPC1 | |
| SCHEMBL6574403 | 0.80 | KMT2A (0.65) | MEN1KMT2ARAB9AALDH1A1NPC1 | |
| SCHEMBL11677217 | 0.80 | MEN1 (0.74) | MEN1KMT2ARAB9AALDH1A1NPC1 | |
| SCHEMBL11677222 | 0.80 | MEN1 (0.74) | MEN1KMT2ARAB9AALDH1A1NPC1 | |
| SCHEMBL12835093 | 0.80 | ALDH1A1 (0.79) | MEN1KMT2ARAB9AALDH1A1NPC1 | |
| SCHEMBL9312293 | 0.79 | MEN1 (0.73) | MEN1KMT2ARAB9AALDH1A1NPC1 | |
| SCHEMBL11654124 | 0.79 | RAB9A (0.71) | MEN1KMT2ARAB9AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605476-A | Substituted tricyclic compounds | 鲁宾有限公司（IN） | 2023-01-13 | — | — | CN | disclosed |