Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | JAK2 | O60674 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL897950 | 0.89 | GAA (0.67) | GAAJAK2LMNAMAPTDRD2 | |
| SCHEMBL19825667 | 0.82 | MAPT (0.63) | GAAJAK2LMNAMAPTDRD2 | |
| SCHEMBL2637278 | 0.80 | GAA (0.95) | GAAJAK2LMNAMAPTDRD2 | |
| SCHEMBL983635 | 0.78 | SLC6A2 (0.47) | GAAJAK2LMNAMAPTHRH1 | |
| SCHEMBL5621969 | 0.78 | GAA (0.82) | GAAJAK2LMNAMAPTDRD2 | |
| SCHEMBL9045649 | 0.78 | GAA (0.82) | GAAJAK2LMNAMAPTDRD2 | |
| SCHEMBL9547811 | 0.77 | LMNA (0.51) | GAAJAK2LMNAMAPTDRD2 | |
| SCHEMBL30408898 | 0.77 | GAA (0.67) | GAAJAK2LMNAMAPTDRD2 | |
| SCHEMBL1833210 | 0.77 | GAA (0.67) | GAAJAK2LMNAMAPTDRD2 | |
| SCHEMBL11705264 | 0.77 | HRH1 (0.56) | GAADRD2DRD4DRD3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2405015-A2 | Soluble hyaluronidase glycoprotein (sHASEGP), process for preparing the same, uses and pharmaceutical compositions comprising thereof | Halozyme, Inc. (US) | 2012-01-11 | — | — | EP | disclosed |
| EP-2330213-A1 | Soluble hyaluronidase glycoprotein (sHASEGP), process for preparing the same, uses and pharmaceutical compositions comprising thereof | Halozyme, Inc. (US) | 2011-06-08 | — | — | EP | disclosed |
| EP-2311973-A1 | Soluble hyaluronidase glycoprotein (sHASEGP), process for preparing the same, uses and pharmaceutical compositions comprising thereof | Halozyme, Inc. (US) | 2011-04-20 | — | — | EP | disclosed |